The role of the ATP binding cassette transporter A1 (ABCA1) in maintaining cellular lipid
homeostasis in cardiovascular disease is well established. More recently, the important …

Hyperlipidemia characterized by abnormal deposition of cholesterol in arteries can cause
atherosclerosis and coronary artery occlusion, leading to atherosclerotic coronary heart …

Previous work has reported the important links between cellular bioenergetics and the
development of chronic kidney disease, highlighting the potential for targeting metabolic …

Atherosclerosis is an inflammatory disease initiated by endothelial activation, in which
lipoprotein, cholesterol, extracellular matrix, and various types of immune and non-immune …

AgRP neurons drive hunger, and excessive nutrient intake is the primary driver of obesity
and associated metabolic disorders. While many factors impacting central regulation of …

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. In
recent decades, clinical research has made significant advances, resulting in improved …

Atherosclerosis remains the leading cause of mortality and morbidity worldwide
characterized by the deposition of lipids and fibrous elements in the form of atheroma …

Atherosclerosis is a disease of large-and medium-sized arteries that is caused by
cholesterol accumulation in arterial intimal cells, including macrophages and smooth muscle …

Coronary heart disease (CHD) with atherosclerosis is the leading cause of death worldwide.
ABCA1 and ABCG1 promote cholesterol efflux to suppress foam cell generation and reduce …

Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic
inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol …