Atherosclerosis is the leading cause of death worldwide. APE1/Ref-1 and ABCA1 play key
roles in the progression of atherosclerosis. APE1/Ref-1 suppresses atherosclerosis via …

Abstract Objective Angiopoietin-1 (Ang-1), a secreted protein, mainly regulates
angiogenesis. Ang-1 has been shown to promote the development of atherosclerosis …

Dysfunctional hepatic metabolism has been linked to numerous diseases, including non-
alcoholic fatty liver disease, the most common chronic liver disorder worldwide, which can …

Background Recent studies have focused on the potential role of epicardial adipose tissue
(EAT) in the development of coronary artery disease (CAD). ABCA1 and ABCG1 …

Atherosclerosis is the leading cause of cardiovascular disease (CVD) and the leading
reason behind mortality and morbidity in Western countries. The role of long noncoding …

Atheroprotective properties of human plasma high-density lipoproteins (HDLs) are
determined by their involvement in reverse cholesterol transport (RCT) from the macrophage …

Background and Purpose Atherosclerosis, resulting from lipid dysregulation and vascular
inflammation, causes atherosclerotic cardiovascular disease (ASCVD), which contributes to …

Objective: To seek out the effect of curcumin on cholesterol efflux in THP-1 macrophages
and clarify its specific mechanism. Methods: THP-1 macrophages were cultured with …

Lipids are hydrophobic and amphiphilic molecules involved in diverse functions such as
membrane structure, energy metabolism, immunity, and signaling. However, altered intra …

Chronic systemic inflammation is associated with an increased risk of cardiovascular
disease in an environment of low low-density lipoprotein (LDL) and low total cholesterol and …