Immunometabolism is a growing field that centers on a core paradigm: perturbations in
metabolism alter a cell's biological response in immunity and, likewise, inflammatory signals …

Hypoxia and tissue acidification occur in the macrophage-rich regions of advanced
atherosclerotic lesions due to the higher oxygen demand of activated immune cells and …

High-density lipoproteins (HDL) are key players in cholesterol metabolism homeostasis
since they are responsible for transporting excess cholesterol from peripheral tissues to the …

demetrios.braddock@yale.edu Page 1 Supplemental Methods, Figures, and Figure Legends
for: A dual-acting DNASE1 biologic prevents autoimmunity and death in genetic and …

Atherosclerosis is a condition caused by cholesterol accumulating in arterial intimal cells
and is a disease that kills more people in the United States and globally than any other …

High-density lipoproteins (HDL) are key players in cholesterol metabolism homeostasis
since they are responsible for transporting excess cholesterol from peripheral tissues to the …

Background: Atherosclerosis is a major pathogenic factor in cardiovascular diseases during
the aging process. Foam cell formation and endothelial dysfunction play a key role in the …

Atherosclerotic vascular disease is one of the leading causes of death throughout the world.
High-density lipoprotein cholesterol (HDL-C) is traditionally considered as “good” …