SH Duttke, C Guzman, M Chang, NP Delos Santos… - Nature, 2024 - nature.com
Patterns of transcriptional activity are encoded in our genome through regulatory elements such as promoters or enhancers that, paradoxically, contain similar assortments of …
Highlights•Synthetic biology applications rely on collections of sequence-verified DNA parts.•The choice of DNA parts in a construct determines its utility and effectiveness.• …
J Pozojevic, R Sivaprasad, J Laß, F Haarich, J Trinh… - Scientific Reports, 2024 - nature.com
Androgen insensitivity syndrome (AIS) is a difference of sex development (DSD) characterized by different degrees of undervirilization in individuals with a 46, XY karyotype …
Medicago truncatula, model legume and alfalfa relative, has served as an essential resource for advancing our understanding of legume physiology, functional genetics, and crop …
A Dueñas Rey, M del Pozo Valero, M Bouckaert… - Genome Medicine, 2024 - Springer
Abstract Background 5'untranslated regions (5'UTRs) are essential modulators of protein translation. Predicting the impact of 5'UTR variants is challenging and rarely performed in …
L Ouyang, J Wang, H Zhu, Y Wu… - Journal of Agricultural and …, 2024 - ACS Publications
Lysine lactylation (Kla) is a kind of novel post-translational modification (PTM) that participates in gene expression and various metabolic processes. Nannochloropsis has a …
A García, G Maldonado, G Hernández - Trends in Cell Biology, 2024 - cell.com
High-risk human papillomaviruses (HPVs) cause most cases of cervical cancer, a disease with an increasing impact worldwide. Recent studies have shown that the synthesis of viral …
J Zeng, K Song, J Wang, H Wen, J Zhou, T Ni… - Microbial Cell …, 2024 - Springer
Background The 5´ untranslated region (5´ UTR) plays a key role in regulating translation efficiency and mRNA stability, making it a favored target in genetic engineering and …
Z Fu, Y Yuan - Pharmacological Research, 2024 - Elsevier
TNFα-induced protein 2 (TNFAIP2), upregulated under TNFα stimulation, was initially thought to participate in angiogenesis. Still, more and more studies have found that TNFAIP2 …