Hallmarks of Severe COVID-19 Pathogenesis: A Pas de Deux Between Viral and Host Factors
R Rovito, M Augello, A Ben-Haim, V Bono… - Frontiers in …, 2022 - frontiersin.org
Two years into Coronavirus Disease 2019 (COVID-19) pandemic, a comprehensive
characterization of the pathogenesis of severe and critical forms of COVID-19 is still missing …
characterization of the pathogenesis of severe and critical forms of COVID-19 is still missing …
Deconvoluting the T cell response to SARS-coV-2: specificity versus chance and cognate cross-reactivity
AA Lehmann, GA Kirchenbaum, T Zhang… - Frontiers in …, 2021 - frontiersin.org
SARS-CoV-2 infection takes a mild or clinically inapparent course in the majority of humans
who contract this virus. After such individuals have cleared the virus, only the detection of …
who contract this virus. After such individuals have cleared the virus, only the detection of …
Immune response to SARS-CoV-2 infection in obesity and T2D: literature review
J Pérez-Galarza, C Prócel, C Cañadas, D Aguirre… - Vaccines, 2021 - mdpi.com
In December 2019, a novel coronavirus known as SARS-CoV-2 was first detected in Wuhan,
China, causing outbreaks of the coronavirus disease COVID-19 that has now spread …
China, causing outbreaks of the coronavirus disease COVID-19 that has now spread …
SARS-CoV-2-specific T cells generated for adoptive immunotherapy are capable of recognizing multiple SARS-CoV-2 variants
A Panikkar, KE Lineburg, J Raju, KY Chew… - PloS …, 2022 - journals.plos.org
Adoptive T-cell immunotherapy has provided promising results in the treatment of viral
complications in humans, particularly in the context of immunocompromised patients who …
complications in humans, particularly in the context of immunocompromised patients who …
The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent manner
DJ Hamelin, D Fournelle, JC Grenier, J Schockaert… - Cell systems, 2022 - cell.com
The rapid, global dispersion of SARS-CoV-2 has led to the emergence of a diverse range of
variants. Here, we describe how the mutational landscape of SARS-CoV-2 has shaped HLA …
variants. Here, we describe how the mutational landscape of SARS-CoV-2 has shaped HLA …
Clinical characteristics and predictive value of lower CD4+T cell level in patients with moderate and severe COVID-19: a multicenter retrospective study
X Wen, D Jiang, L Gao, J Zhou, J Xiao, X Cheng… - BMC infectious …, 2021 - Springer
Abstract Background In December 2019, coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, Hubei …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, Hubei …
[HTML][HTML] CD8+ PD-L1+ CXCR3+ polyfunctional T cell abundances are associated with survival in critical SARS-CoV-2–infected patients
L Adam, P Rosenbaum, P Quentric, C Parizot… - JCI insight, 2021 - ncbi.nlm.nih.gov
The importance of the adaptive T cell response in the control and resolution of viral infection
has been well established. However, the nature of T cell–mediated viral control mechanisms …
has been well established. However, the nature of T cell–mediated viral control mechanisms …
Potent induction of humoral and cellular immunity after bivalent BA. 4/5 mRNA vaccination in dialysis patients
S Bronder, J Mihm, R Urschel, V Klemis, T Schmidt… - npj Vaccines, 2024 - nature.com
Abstract Knowledge on immunogenicity of the bivalent Omicron BA. 4/5 vaccine in dialysis
patients and the effect of a previous infection is limited. Therefore, vaccine-induced humoral …
patients and the effect of a previous infection is limited. Therefore, vaccine-induced humoral …
Quality of T-cell response to SARS-CoV-2 mRNA vaccine in ART-treated PLWH
E Tortellini, MA Zingaropoli, G Mancarella… - International Journal of …, 2022 - mdpi.com
We investigated specific humoral and T-cell responses in people living with HIV (PLWH)
before (T0), after two (T1) and after six months (T2) from the third dose of the BNT162b2 …
before (T0), after two (T1) and after six months (T2) from the third dose of the BNT162b2 …
Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with …
J Heide, S Schulte, M Kohsar, TT Brehm… - PLoS …, 2021 - journals.plos.org
The aim of this study was to define the breadth and specificity of dominant SARS-CoV-2-
specific T cell epitopes using a comprehensive set of 135 overlapping 15-mer peptides …
specific T cell epitopes using a comprehensive set of 135 overlapping 15-mer peptides …