A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
JN Søndergaard, J Tulyeu, R Edahiro… - Proceedings of the …, 2023 - National Acad Sciences
Sex-biased humoral immune responses to COVID-19 patients have been observed, but the
cellular basis for this is not understood. Using single-cell proteomics by mass cytometry, we …
cellular basis for this is not understood. Using single-cell proteomics by mass cytometry, we …
High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from …
PG Coulon, S Prakash, NR Dhanushkodi… - Frontiers in …, 2024 - frontiersin.org
Background Cross-reactive SARS-CoV-2-specific memory CD4+ and CD8+ T cells are
present in up to 50% of unexposed, pre-pandemic, healthy individuals (UPPHIs). However …
present in up to 50% of unexposed, pre-pandemic, healthy individuals (UPPHIs). However …
Low pre-existing endemic human coronavirus (HCoV-NL63)-specific T cell frequencies are associated with impaired SARS-CoV-2-specific T cell responses in people …
TL Ng'uni, V Musale, T Nkosi, J Mandolo… - Frontiers in …, 2024 - frontiersin.org
Background Understanding how HIV affects SARS-CoV-2 immunity is crucial for managing
COVID-19 in sub-Saharan populations due to frequent coinfections. Our previous research …
COVID-19 in sub-Saharan populations due to frequent coinfections. Our previous research …
SARS-CoV-2-reactive IFN-γ-producing CD4+ and CD8+ T cells in blood do not correlate with clinical severity in unvaccinated critically ill COVID-19 patients
B Olea, E Albert, E Giménez, I Torres, P Amat… - Scientific Reports, 2022 - nature.com
We examined the relationship between peripheral blood levels of SARS-CoV-2 S (Spike
protein) 1/M (Membrane protein)-reactive IFN-γ-producing CD4+ and CD8+ T cells, serum …
protein) 1/M (Membrane protein)-reactive IFN-γ-producing CD4+ and CD8+ T cells, serum …
Artificial intelligence and clinical data suggest the T cell-mediated SARS-CoV-2 nonstructural protein intranasal vaccines for global COVID-19 immunity
M Seyran - Vaccine, 2022 - Elsevier
Advanced computational methodologies suggested SARS-CoV-2, nonstructural proteins
ORF1AB, ORF3a, as the source of immunodominant peptides for T cell presentation. T cell …
ORF1AB, ORF3a, as the source of immunodominant peptides for T cell presentation. T cell …
High and Sustained Ex Vivo Frequency but Altered Phenotype of SARS-CoV-2-Specific CD4+ T-Cells in an Anti-CD20-Treated Patient with Prolonged COVID-19
L Cords, M Knapp, R Woost, S Schulte, S Kummer… - Viruses, 2022 - mdpi.com
Here, we longitudinally assessed the ex vivo frequency and phenotype of SARS-CoV-2
membrane protein (aa145–164) epitope-specific CD4+ T-cells of an anti-CD20-treated …
membrane protein (aa145–164) epitope-specific CD4+ T-cells of an anti-CD20-treated …
Antigen-Specific T Cells and SARS-CoV-2 Infection: Current Approaches and Future Possibilities
Z Nova, T Zemanek, N Botek - International Journal of Molecular Sciences, 2022 - mdpi.com
COVID-19, a significant global health threat, appears to be an immune-related disease.
Failure of effective immune responses in initial stages of infection may contribute to …
Failure of effective immune responses in initial stages of infection may contribute to …
Profile of SARS-CoV-2-specific CD4 T cell response: Relationship with disease severity and impact of HIV-1 and active Mycobacterium tuberculosis co-infection
SUMMARY T cells are involved in control of COVID-19, but limited knowledge is available
on the relationship between antigen-specific T cell response and disease severity. Here, we …
on the relationship between antigen-specific T cell response and disease severity. Here, we …
SARS-CoV-2-specific cellular and humoral immunity after bivalent BA. 4/5 COVID-19-vaccination in previously infected and non-infected individuals
R Urschel, S Bronder, V Klemis, S Marx… - Nature …, 2024 - nature.com
Abstract Knowledge is limited as to how prior SARS-CoV-2 infection influences cellular and
humoral immunity after booster-vaccination with bivalent BA. 4/5-adapted mRNA-vaccines …
humoral immunity after booster-vaccination with bivalent BA. 4/5-adapted mRNA-vaccines …
[HTML][HTML] The adaptation of SARS-CoV-2 to humans
E Tosta - Memórias do Instituto Oswaldo Cruz, 2022 - SciELO Brasil
The process of adaptation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) to humans probably had started decades ago, when its ancestor diverged from the bat …
2) to humans probably had started decades ago, when its ancestor diverged from the bat …