De novo rates and selection of schizophrenia-associated copy number variants
BACKGROUND: At least 10 large and rare recurrent DNA copy number variants (CNVs)
have been identified as risk factors for schizophrenia and other neurodevelopmental …
have been identified as risk factors for schizophrenia and other neurodevelopmental …
Association between arachidonic acid and the risk of schizophrenia: a cross-national study and Mendelian randomization analysis
Y Gao, X Hu, D Wang, J Jiang, M Li, Y Qing, X Yang… - Nutrients, 2023 - mdpi.com
Polyunsaturated fatty acids (PUFAs), especially long-chain PUFAs (LCPUFAs), are crucial
for both the structural and functional integrity of cells. PUFAs have been reported to be …
for both the structural and functional integrity of cells. PUFAs have been reported to be …
Predictive impact of rare genomic copy number variations in siblings of individuals with autism spectrum disorders
L D'Abate, S Walker, RKC Yuen, K Tammimies… - Nature …, 2019 - nature.com
Identification of genetic biomarkers associated with autism spectrum disorders (ASDs) could
improve recurrence prediction for families with a child with ASD. Here, we describe clinical …
improve recurrence prediction for families with a child with ASD. Here, we describe clinical …
Transcriptome sequencing study implicates immune-related genes differentially expressed in schizophrenia: new data and a meta-analysis
AR Sanders, EI Drigalenko, J Duan, W Moy… - Translational …, 2017 - nature.com
We undertook an RNA sequencing (RNAseq)-based transcriptomic profiling study on
lymphoblastoid cell lines of a European ancestry sample of 529 schizophrenia cases and …
lymphoblastoid cell lines of a European ancestry sample of 529 schizophrenia cases and …
[HTML][HTML] From DNA human sequence to the chromatin higher order organisation and its biological meaning: using biomolecular interaction networks to understand the …
The three-dimensional structure of the human genome has been proven to have a
significant functional impact on gene expression. The high-order spatial chromatin is …
significant functional impact on gene expression. The high-order spatial chromatin is …
MicroRNA dysregulation in neuropsychiatric disorders and cognitive dysfunction
MicroRNAs (miRNA), a class of non-coding RNAs, are emerging as important modulators of
neuronal development, structure and function. A connection has been established between …
neuronal development, structure and function. A connection has been established between …
Genome‐Wide Findings in Schizophrenia and the Role of Gene–Environment Interplay
R Van Winkel, G Esquivel, G Kenis… - CNS neuroscience & …, 2010 - Wiley Online Library
The recent advent of genome‐wide mass‐marker technology has resulted in renewed
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …
Association testing of copy number variants in schizophrenia and autism spectrum disorders
BJ Crespi, HJ Crofts - Journal of neurodevelopmental disorders, 2012 - Springer
Background Autism spectrum disorders and schizophrenia have been associated with an
overlapping set of copy number variant loci, but the nature and degree of overlap in copy …
overlapping set of copy number variant loci, but the nature and degree of overlap in copy …
NDE1 and NDEL1 from genes to (mal) functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness
NJ Bradshaw, MAF Hayashi - Cellular and molecular life sciences, 2017 - Springer
Abstract NDE1 (Nuclear Distribution Element 1, also known as NudE) and NDEL1 (NDE-
Like 1, also known as NudEL) are the mammalian homologues of the fungus nudE gene …
Like 1, also known as NudEL) are the mammalian homologues of the fungus nudE gene …
Integrative analysis of genetic data sets reveals a shared innate immune component in autism spectrum disorder and its co-morbidities
Background Autism spectrum disorder (ASD) is a common neurodevelopmental disorder
that tends to co-occur with other diseases, including asthma, inflammatory bowel disease …
that tends to co-occur with other diseases, including asthma, inflammatory bowel disease …