Dendritic spines are tiny membrane specialization forming the postsynaptic part of most
excitatory synapses. They have been suggested to play a crucial role in regulating synaptic …

CDKL5 deficiency disorder (CDD) is an X-linked brain disorder of young children and is
caused by pathogenic variants in the cyclin-dependent kinase-like 5 (CDKL5) gene …

Brain-derived neurotrophic factor (BDNF) and its tropomyosin-related kinase B receptor
(TrkB) are expressed in human osteoblasts and mediate fracture healing. BDNF/TrkB …

Early-onset epileptic encephalopathies are severe disorders often associated with specific
genetic mutations. In this context, the CDKL5 deficiency disorder (CDD) is a …

Pathological loss-of-function mutations in cyclin-dependent kinase-like 5 (CDKL5) cause
CDKL5 deficiency disorder (CDD), a rare and severe neurodevelopmental disorder …

CDKL5 deficiency disorder (CDD), a rare and severe neurodevelopmental disease caused
by mutations in the X-linked CDKL 5 gene, is characterized by early-onset epilepsy …

Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a rare
neurodevelopmental disease caused by mutations in the X-linked CDKL5 gene. CDD is …

CDKL5 deficiency disorder (CDD) is a severe epileptic encephalopathy resulting from
pathological mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene …

The clinical phenotype of Cyclin-Dependent Kinase-Like 5 (CDKL5) deficiency disorder
(CDD) has been delineated but neuroimaging features have not been systematically …

Rett syndrome (RTT) and CDKL5 deficiency disorder (CDD) are two rare X-linked
developmental brain disorders with overlapping but distinct phenotypic features. This review …