Live imaging is a powerful tool, enabling scientists to observe living organisms in real time.
In particular, when combined with fluorescence microscopy, live imaging allows the …

Light-sheet fluorescence microscopy has transformed our ability to visualize and
quantitatively measure biological processes rapidly and over long time periods. In this …

In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images.
Existing cell segmentation methods are often tailored to specific modalities or require …

Towards foundation models of biological image segmentation | Nature Methods Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation
of the spatial localization of transcripts and related analyses in various applications for …

The ribotoxic stress response (RSR) is a signaling pathway in which the p38-and c-Jun N-
terminal kinase (JNK)–activating mitogen-activated protein kinase kinase kinase (MAP3K) …

A key step toward biologically interpretable analysis of microscopy image-based assays is
rigorous quantitative validation with metrics appropriate for the particular application in use …

The field of bioimage analysis is poised for a major transformation, owing to advancements
in imaging technologies and artificial intelligence. The emergence of multimodal foundation …

BACKGROUND: Cardiomyopathy is characterized by the pathological accumulation of
resident cardiac fibroblasts that deposit ECM (extracellular matrix) and generate a fibrotic …