[HTML][HTML] A mathematical modeling of COVID-19 treatment strategies utilizing the Laplace Adomian decomposition method

MO Olayiwola, AI Alaje, AO Yunus… - Results in Control and …, 2024 - Elsevier
This study aims to assess the effectiveness of recent advancements in COVID-19 treatment,
specifically antiviral medicines and monoclonal antibodies, in curbing the virus's spread. We …

Modeling the transmission mitigation impact of testing for infectious diseases

C Middleton, DB Larremore - Science Advances, 2024 - science.org
A fundamental question of any program focused on the testing and timely diagnosis of a
communicable disease is its effectiveness in reducing transmission. Here, we introduce …

Accelerating therapeutics development during a pandemic: population pharmacokinetics of the long-acting antibody combination AZD7442 (tixagevimab/cilgavimab) …

LE Clegg, O Stepanov, H Schmidt, W Tang… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
ABSTRACT AZD7442 is a combination of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2)-neutralizing antibodies, tixagevimab and cilgavimab, developed for pre …

Virus-mediated cell fusion of SARS-CoV-2 variants

A Amidei, HM Dobrovolny - Mathematical Biosciences, 2024 - Elsevier
SARS-CoV-2 has the ability to form large multi-nucleated cells known as syncytia. Little is
known about how syncytia affect the dynamics of the infection or severity of the disease. In …

Development of a SARS‐CoV‐2 viral dynamic model for patients with COVID‐19 based on the amount of viral RNA and viral titer

D Yamaguchi, R Shimizu… - CPT: Pharmacometrics & …, 2024 - Wiley Online Library
The target‐cell limited model, which is one of the mathematical modeling approaches
providing a quantitative understanding of viral dynamics, has been applied to describe viral …