Aptamers are nucleic acid analogues of antibodies with high affinity to different targets, such
as cells, viruses, proteins, inorganic materials, and coenzymes. Empirical approaches allow …

Aptamers are short single-stranded DNA, RNA, or synthetic Xeno nucleic acids (XNA)
molecules that can interact with corresponding targets with high affinity. Owing to their …

During an epidemic or pandemic, the primary task is to rapidly develop precise diagnostic
approaches and effective therapeutics. Oligonucleotide aptamer-based pathogen detection …

An aptamer is a single-stranded DNA or RNA that binds to a specific target with high binding
affinity. Aptamers are developed through the process of systematic evolution of ligands by …

Here we review recent developments in mass spectrometry that have enabled its growing
contribution to the field of structural virology. Evidently, there is a strong renewed general …

The SARS-CoV-2 virus is currently the most serious challenge to global public health. Its
emergence has severely disrupted the functioning of health services and the economic and …

Infectious diseases are considered as a pressing challenge to global public health. Accurate
and rapid diagnostics tools for early recognition of the pathogen, as well as individualized …

Viral infections cause a host of fatal diseases and seriously affect every form of life from
bacteria to humans. Although most viral infections can receive appropriate treatment thereby …

Nucleic acid aptamers are single-stranded DNA or RNA molecules selected in vitro that can
bind to a broad range of targets with high affinity and specificity. As promising alternatives to …

Noncanonical base pairs contribute crucially to the three-dimensional architecture of large
RNA molecules; however, how to accurately model them remains an open challenge in RNA …