Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Sufficient ocular bioavailability is often considered a challenge by the researchers, due to
the complex structure of the eye and its protective physiological mechanisms. In addition, the …

Due to its poor solubility and systemic side effects, gefitinib (Gef) has limited application in
treatment of lung cancer. In this study, we used design of experiment (DOE) tools to gain the …

Conventional RA treatments required prolonged therapy courses that have been
accompanied with numerous side effects impairing the patient's quality of life. Therefore …

Honokiol is a phytochemical component with a variety of pharmacological properties.
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …

This study aims to develop efficient topical therapy for keratomycosis using
sertaconazolenitrate (STZN)-loaded leciplex (LP). The D-optimal design was used to …

The nanomaterial and related toolkit have promising applications for improving human
health and well-being. Nanobased drug delivery systems use nanoscale materials as …

Chronic ocular diseases can seriously impact the eyes and could potentially result in
blindness or serious vision loss. According to the most recent data from the WHO, there are …

A chitosan-coated luteolin-loaded phytocubosomal system was prepared to improve the
pharmacodynamic performance of luteolin in the treatment of glaucoma and ocular …

Objectives Lipid nanoparticles, as a nucleic acid delivery system, have been used as an
alternative to treat ocular diseases, since they can cross the ocular barrier and efficiently …