This Review describes current knowledge on the epidemiology and causes of child and
adolescent obesity, considerations for assessment, and current management approaches …

Over the past several decades, the incidence of early-onset colorectal cancer (EOCRC; in
patients< 50 years old) has increased at an alarming rate. Although robust and scientifically …

The current and long-term health of 14.4 million children and adolescents is affected by
obesity, 1, 2 making it one of the most common pediatric chronic diseases. 3–5 Long …

Prevalence of childhood obesity has worldwide more than doubled since 1980. Underlying
factors are complex and are far from completely understood. Strategies to prevent childhood …

Background Antibiotics are amongst the most commonly used drugs in children. In addition
to inducing antibiotic resistance, antibiotic exposure has been associated with adverse long …

Sepsis is a leading cause of mortality and morbidity in neonates. Presenting clinical
symptoms are unspecific. Sensitivity and positive predictive value of biomarkers at onset of …

Increased exposure to antibiotics during early childhood increases the risk of antibiotic-
associated dysbiosis, which is associated with reduced diversity of gut microbial species …

Maternal microbiota forms the first infant gut microbial inoculum, and perinatal factors (diet
and use of antibiotics during pregnancy) and/or neonatal factors, like intra partum antibiotics …

Importance The neonatal early-onset sepsis (EOS) calculator is a clinical risk stratification
tool increasingly used to guide the use of empirical antibiotics for newborns. Evidence on …

Obesity is a condition of rising prevalence worldwide, with important socioeconomic
implications, being considered as a growing public health concern. Frequently, obesity …