The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …

The simultaneous intake of food and drugs can have a strong impact on drug release,
absorption, distribution, metabolism and/or elimination and consequently, on the efficacy …

Recently, tremendous progress in synthetic micro/nanomotors in diverse environment has
been made for potential biomedical applications. However, existing micro/nanomotor …

In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …

Oral administration is a pillar of the pharmaceutical industry and yet it remains challenging to
administer hydrophilic therapeutics by the oral route. Smart and controlled oral drug delivery …

Oral administration is the most common route of drug delivery. The absorption of a drug from
the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of …

Mucus is a complex viscoelastic gel and acts as a barrier covering much of the soft tissue in
the human body. High vascularization and accessibility have motivated drug delivery to …

Poorly water-soluble drugs are frequently encountered and present a most challengeable
difficulty in pharmaceutical development. Poor solubility of drugs can lead to suboptimal …

The availability of in vitro tools that are constructed on the basis of a detailed knowledge of
key aspects of gastrointestinal (GI) physiology and their impact on formulation performance …

Oral chemotherapy has been emerging as a hopeful therapeutic regimen for the treatment of
various cancers because of its high safety and convenience, lower costs, and high patient …