Modulation of redox-sensitive transcription factors with polyphenols as pathogenetically grounded approach in therapy of systemic inflammatory response

V Kostenko, O Akimov, O Gutnik, H Kostenko… - Heliyon, 2023 - cell.com
One of the adverse outcomes of acute inflammatory response is progressing to the chronic
stage or transforming into an aggressive process, which can develop rapidly and result in …

Current understanding of polyphenols to enhance bioavailability for better therapies

M Aatif - Biomedicines, 2023 - mdpi.com
In recent years, plant polyphenols have become a popular focus for the development of
novel functional foods. Polyphenols, a class of bioactive compounds, including flavonoids …

Drug design strategies that aim to improve the low solubility and poor bioavailability conundrum in quercetin derivatives

SR Alizadeh, N Savadkouhi… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Scientists are especially interested in polyphenols, particularly flavonoids.
Quercetin, a flavonoid, has demonstrated various therapeutic properties, such as …

[HTML][HTML] Scientific evidences of anticancer potential of medicinal plants

S Chandra, M Gahlot, AN Choudhary, S Palai… - Food Chemistry …, 2023 - Elsevier
Cancer being a life treating ailment is the second reason of death universally. The growing
threats of medication-resistant cancers indicates an crucial need for the improvement of …

Liposomes and phytosomes: nanocarrier systems and their applications for the delivery of phytoconstituents

Y Dutt, RP Pandey, M Dutt, A Gupta, A Vibhuti… - Coordination Chemistry …, 2023 - Elsevier
Phytochemicals, such as terpenes, polyphenols, and tannins, have been used in history, for
the treatment of illnesses and fever. Phytochemicals are easily available in nature, can be …

Resveratrol, epigallocatechin gallate and curcumin for cancer therapy: challenges from their pro-apoptotic properties

A Chimento, M D'Amico, A De Luca, FL Conforti… - Life, 2023 - mdpi.com
Plant-derived bioactive compounds are gaining wide attention for their multiple health-
promoting activities and in particular for their anti-cancer properties. Several studies have …

The combination of bioavailable concentrations of Curcumin and Resveratrol shapes Immune responses while retaining the ability to Reduce Cancer Cell Survival

C Focaccetti, C Palumbo, M Benvenuto… - International Journal of …, 2023 - mdpi.com
The polyphenols Curcumin (CUR) and Resveratrol (RES) are widely described for their
antitumoral effects. However, their low bioavailability is a drawback for their use in therapy …

[HTML][HTML] Resveratrol as a privileged molecule with antioxidant activity

T Constantinescu, AG Mihis - Food Chemistry Advances, 2023 - Elsevier
Oxidative stress has a significant impact on the occurrence of many chronic diseases.
Antioxidants have ability to prevent, postpone or treat effects of free radicals. Resveratrol is a …

Combination chemotherapy with selected polyphenols in preclinical and clinical studies—An update overview

C Jakobušić Brala, A Karković Marković, A Kugić… - Molecules, 2023 - mdpi.com
This review article describes studies published over the past five years on the combination
of polyphenols, which are the most studied in the field of anticancer effects (curcumin …

Inflammation in Prostate Cancer: Exploring the Promising Role of Phenolic Compounds as an Innovative Therapeutic Approach

R Fernandes, C Costa, R Fernandes, AN Barros - Biomedicines, 2023 - mdpi.com
Prostate cancer (PCa) remains a significant global health concern, being a major cause of
cancer morbidity and mortality worldwide. Furthermore, profound understanding of the …