In recent years, tumor immunotherapy has made significant progress. However, tumor
immunotherapy, particularly immune checkpoint inhibitors (eg, PD-1/PD-L1 inhibitors) …

Anti-angiogenic therapies (AATs) are used to treat different types of cancers. However, their
success is limited owing to insufficient efficacy and resistance. Recently, single-cell omics …

Cancers are a group of heterogeneous diseases characterized by the acquisition of
functional capabilities during the transition from a normal to a neoplastic state. Powerful …

Cancer is a complex disease that causes abnormal genetic changes and unchecked cellular
growth. It also causes a disruption in the normal regulatory processes that leads to the …

As an emerging sequencing technology, single-cell RNA sequencing (scRNA-Seq) has
become a powerful tool for describing cell subpopulation classification and cell …

Gastric carcinoma is a highly malignant tumor that still lacks effective molecular targets.
Heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) is an essential oncogenic …

Human gastric cancer is a highly lethal disease, but the underlying multiomic molecular
signatures remain largely unclear. Here, we performed multi-regional sampling, parallel …

Gastric cancer is one of the most serious malignant tumor and threatens the health of people
worldwide. Its heterogeneity leaves many clinical problems unsolved. To treat it effectively …

Conventional tumor models have critical shortcomings in that they lack the complexity of the
human stroma. The heterogeneous stroma is a central compartment of the tumor …

Single-cell RNA sequencing (scRNA-seq) and bulk RNA sequencing (bulk RNA-seq) are
increasingly used for screening genes involved in carcinogenesis due to their capacity for …