With approximately 50% of all cancer patients receiving radiation therapy at some point in
their treatment, increasing the sensitivity of tumor cells to the lethal effects of irradiation has …

Radioresistance is a major obstacle in radiotherapy for cancer, and strategies are needed to
overcome this problem. Currently, radiotherapy combined with targeted therapy such as …

Fas is a member of the tumour necrosis factor receptor superfamily. Fas-mediated apoptosis
is an essential mechanism protecting against skin cancer. Activation of Fas by specific …

Purpose: Various sources of radiation including radiofrequency, electromagnetic radiation
(EMR), low-dose X-radiation, low-level microwave radiation and ionizing radiation (IR) are …

Sunburn cell (SBC) formation in the epidermis is a characteristic consequence of ultraviolet
radiation (UVR) exposure at doses around or above the minimum erythema dose. SBC have …

Background: Ultraviolet (UV) radiation is the major environmental harmful factor that affects
human skin. UVB radiation is known to be a potent inducer of reactive oxygen species …

Mycosis fungoides (MF) is the most frequent manifestation of cutaneous T cell lymphoma but
its cause and pathophysiology remain unclear. Because progression of lesions is …

The CD95 (also called APO-1 or Fas) system plays a major role in the induction of apoptosis
in lymphoid and nonlymphoid tissues in response to a variety of extracellular signals …

Fas Ligand (FasL) is a member of the TNF superfamily that induces apoptosis in susceptible
cells upon cross-linking of its own receptor, Fas (Apo-1/CD95). FasL-induced apoptosis …

Intraperitoneal injection of the hydrocarbon oil pristane into normal mice leads to a lupus-
like autoimmune syndrome. Although advances in defining the roles of cellular and humoral …