Phototherapeutic modalities, including narrowband-UVB, broadband-UVB, PUVA
photochemotherapy, and excimer laser therapy are valuable tools that can be used for …

Spontaneous or therapeutic induction of T cell apoptosis plays a critical role in establishing
transplantation tolerance and maintaining remission of autoimmune diseases. We …

UVB irradiation of the skin causes immunosuppression and Ag-specific tolerance in which
Langerhans cells (LC) are involved. We tested the effect of UVB on LC that had migrated out …

Serum starvation is a typical way for inducing tumor cell apoptosis and stress. Asymmetric
dimethylarginine (ADMA) is an endogenous metabolite. Our previous study reveals the …

We have recently reported that activation of protein kinase C (PKC) plays a negative role in
CD95-mediated apoptosis in human T cell lines. Here we present data indicating that …

Menadione, or vitamin K3 (VK3), a potent oxidative stress inducer, has been recently used
as an effective and remarkably safe cytotoxic drug for treatment of several human tumors …

Arachidonic acid (AA)-induced apoptotic death of human leukemia U937 cells was
characteristic of increase in intracellular Ca2+ concentration ([Ca2+] i), ROS generation …

Ultraviolet (UV) A-1 (340–400 nm) radiation is highly effective in inducing apoptosis in skin-
infiltrating T cells and thereby exerts beneficial effects in patients with T cell-mediated skin …

Modification of major lipid raft components, such as cholesterol and ceramide, plays a role in
regulation of programmed cell death under various stimuli. However, the relationship …

Dendritic cells (DCs) play a central role in the initiation and regulation of the immune
response. The modalities by which DCs are committed to undergo apoptosis are poorly …