Selenium: an antioxidant with a critical role in anti-aging

G Bjørklund, M Shanaida, R Lysiuk, H Antonyak… - Molecules, 2022 - mdpi.com
Aging is characterized by an imbalance between damage inflicted by reactive oxygen
species (ROS) and the antioxidative defenses of the organism. As a significant nutritional …

The impact of selenium deficiency on cardiovascular function

BK Shimada, N Alfulaij, LA Seale - International journal of molecular …, 2021 - mdpi.com
Selenium (Se) is an essential trace element that is necessary for various metabolic
processes, including protection against oxidative stress, and proper cardiovascular function …

[HTML][HTML] Deiodinases control local cellular and systemic thyroid hormone availability

J Köhrle, C Frädrich - Free Radical Biology and Medicine, 2022 - Elsevier
Iodothyronine deiodinases (DIO) are a family of selenoproteins controlling systemic and
local availability of the major thyroid hormone l-thyroxine (T4), a prohormone secreted by the …

Selenoprotein P–Selenium transport protein, enzyme and biomarker of selenium status

L Schomburg - Free Radical Biology and Medicine, 2022 - Elsevier
The habitual intake of selenium (Se) varies strongly around the world, and many people are
at risk of inadequate supply and health risks from Se deficiency. Within the human organism …

Selenium status and its antioxidant role in metabolic diseases

J Huang, L Xie, A Song, C Zhang - Oxidative Medicine and …, 2022 - Wiley Online Library
Selenium (Se), in the form of selenoproteins, is an essential micronutrient that plays an
important role in human health and disease. To date, there are at least 25 selenoproteins in …

[HTML][HTML] Autoantibodies to selenoprotein P in chronic fatigue syndrome suggest selenium transport impairment and acquired resistance to thyroid hormone

Q Sun, E Oltra, DAJ Dijck-Brouwer, TS Chillon… - Redox Biology, 2023 - Elsevier
Abstract Chronic Fatigue Syndrome (CFS) presents with symptoms of hypothyroidism,
including mental and physical fatigue, poor sleep, depression, and anxiety. However, thyroid …

Micronutrient deficiencies in heart failure: Mitochondrial dysfunction as a common pathophysiological mechanism?

N Bomer, MG Pavez‐Giani… - Journal of Internal …, 2022 - Wiley Online Library
Heart failure is a devastating clinical syndrome, but current therapies are unable to abolish
the disease burden. New strategies to treat or prevent heart failure are urgently needed …

[HTML][HTML] Selenium deficiency

AP Shreenath, MF Hashmi, J Dooley - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Selenium Deficiency - StatPearls - NCBI Bookshelf US flag An official website of the United
States government Here's how you know NIH NLM Logo Access keys NCBI Homepage …

The role of selected trace elements in oxidoreductive homeostasis in patients with thyroid diseases

M Wróblewski, J Wróblewska, J Nuszkiewicz… - International journal of …, 2023 - mdpi.com
Impaired levels of selenium (Se), zinc (Zn), copper (Cu), iron (Fe), manganese (Mn) and
iodine (I) in the organism may adversely affect the thyroid endocrine system. These trace …

High selenium levels associate with reduced risk of mortality and new‐onset heart failure: data from PREVEND

AA Al‐Mubarak, N Grote Beverborg… - European Journal of …, 2022 - Wiley Online Library
Aim To elucidate the relationship between serum selenium levels and the risk of mortality
and new‐onset heart failure (HF) in the general adult population. Methods and results …