Genomic structural variation (SV) affects genetic and phenotypic characteristics in diverse
organisms, but the lack of reliable methods to detect SV has hindered genetic analysis. We …

Large-scale imputation reference panels are currently available and have contributed to
efficient genome-wide association studies through genotype imputation. However, whether …

As a vital anthropometric characteristic, human height information not only helps to
understand overall developmental status and genetic risk factors, but is also important for …

Multiple sclerosis (MS) is a complex and demyelinating disease of the central nervous
system. One of the challenges of the post-genome-wide association studies (GWAS) era is …

In recent years, genome-wide association studies have shed light on the genetics of early
growth and its links with later-life health outcomes. Large-scale datasets and meta-analyses …

Background Domestication of the rabbit (Oryctolagus cuniculus) has led to a multi-purpose
species that includes many breeds and lines with a broad phenotypic diversity, mainly for …

Ossification of the posterior longitudinal ligament of the spine (OPLL) is an intractable
disease leading to severe neurological deficits. Its etiology and pathogenesis are primarily …

The spatial distribution of genetic variants is jointly determined by geography, past
demographic processes, natural selection, and its interplay with environmental variation. A …

Background and aims Obesity is one of the leading causes of non-communicable diseases
(NCD). Thus, NCD risk varies in obese individuals based on the location of their fat depots; …

Aim Previous studies have provided evidence linking the DPEP1 gene to the risk of
osteoarthritis (OA) in Europeans. In this study, we aimed to examine the relationship …