How COVID-19 induces cytokine storm with high mortality

S Hojyo, M Uchida, K Tanaka, R Hasebe… - Inflammation and …, 2020 - Springer
The newly emerging coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China, but …

D-dimer concentrations and COVID-19 severity: a systematic review and meta-analysis

P Paliogiannis, AA Mangoni, P Dettori… - Frontiers in public …, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a recently described infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since late 2019, COVID …

Two important controversial risk factors in SARS-CoV-2 infection: obesity and smoking

AB Engin, ED Engin, A Engin - Environmental toxicology and …, 2020 - Elsevier
The effects of obesity and smoking in the coronavirus disease 2019 (COVID-19) pandemic
remain controversial. Angiotensin converting enzyme 2 (ACE2), a component of the renin …

Serum proteomics in COVID-19 patients: altered coagulation and complement status as a function of IL-6 level

A D'Alessandro, T Thomas… - Journal of proteome …, 2020 - ACS Publications
Over 5 million people around the world have tested positive for the beta coronavirus SARS-
CoV-2 as of May 29, 2020, a third of which are in the United States alone. These infections …

Clinical characteristics, laboratory outcome characteristics, comorbidities, and complications of related COVID-19 deceased: a systematic review and meta-analysis

P Qiu, Y Zhou, F Wang, H Wang, M Zhang… - Aging clinical and …, 2020 - Springer
Background At present, novel coronavirus disease 2019 (COVID-19) has become a serious
global public health problem. The current meta-analysis aimed to find risk factors for the …

COVID-19, cytokines, inflammation, and spices: How are they related?

AB Kunnumakkara, V Rana, D Parama, K Banik… - Life sciences, 2021 - Elsevier
Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …

Antioxidant, anti-inflammatory and immunomodulatory roles of vitamins in COVID-19 therapy

AM Pisoschi, A Pop, F Iordache, L Stanca… - European Journal of …, 2022 - Elsevier
Abstract oxidative stress is caused by an abundant generation of reactive oxygen species,
associated to a diminished capacity of the endogenous systems of the organism to …

COVID-19 in relation to hyperglycemia and diabetes mellitus

HM Al-Kuraishy, AI Al-Gareeb, M Alblihed… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19), triggered by the severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), may lead to extrapulmonary manifestations like diabetes …

[HTML][HTML] A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients

SM Morrissey, AE Geller, X Hu, D Tieri, C Ding… - JCI insight, 2021 - ncbi.nlm.nih.gov
Abstract SARS coronavirus 2 (SARS-CoV-2) is a novel viral pathogen that causes a clinical
disease called coronavirus disease 2019 (COVID-19). Although most COVID-19 cases are …

The role of IL-6 in coronavirus, especially in COVID-19

X Wang, G Tang, Y Liu, L Zhang, B Chen… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infects both people and
animals and may cause significant respiratory problems, including lung illness: Corona …