IL-6 inhibitors in the treatment of serious COVID-19: a promising therapy?

S Atal, Z Fatima - Pharmaceutical medicine, 2020 - Springer
At present, there are no proven agents for treatment of coronavirus disease (COVID-19). The
available evidence has not allowed guidelines to clearly recommend any drugs outside the …

Safety and efficacy of anti-il6-receptor tocilizumab use in severe and critical patients affected by coronavirus disease 2019: A comparative analysis

R Rossotti, G Travi, N Ughi, M Corradin, C Baiguera… - Journal of Infection, 2020 - Elsevier
Background As the novel SARS-CoV-2 pandemic occurred, no specific treatment was yet
available. Inflammatory response secondary to viral infection might be the driver of severe …

Vitamin D supplementation in COVID-19 patients: a clinical case series

KC Ohaegbulam, M Swalih, P Patel… - American journal of …, 2020 - journals.lww.com
Background: Coronavirus disease 2019 (COVID-19) has infected more than 4.4 million
people and caused more than 300,000 deaths partly through acute respiratory distress …

[HTML][HTML] Clinical characteristics and outcomes of patients hospitalized for COVID-19 in Africa: early insights from the Democratic Republic of the Congo

JB Nachega, DK Ishoso, JO Otokoye… - The American journal …, 2020 - ncbi.nlm.nih.gov
Little is known about the clinical features and outcomes of SARS-CoV-2 infection in Africa.
We conducted a retrospective cohort study of patients hospitalized for COVID-19 between …

Impacto del confinamiento por COVID-19 en la calidad de vida y salud mental

CL Ballena, L Cabrejos, Y Davila… - Revista del Cuerpo …, 2021 - scielo.org.pe
Introducción: La pandemia por SARS-Cov-2 ha tenido un impacto negativo en múltiples
aspectos de la vida humana, tanto en lo físico, psicológico, económico, social y cultural. Las …

The role of biosensors in coronavirus disease-2019 outbreak

M Asif, M Ajmal, G Ashraf, N Muhammad, A Aziz… - Current Opinion in …, 2020 - Elsevier
Herein, we have summarized and argued about biomarkers and indicators used for the
detection of severe acute respiratory syndrome coronavirus 2. Antibody detection methods …

[HTML][HTML] The role of Interleukin 6 inhibitors in therapy of severe COVID-19

E Nasonov, M Samsonov - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cytokine storm syndrome (CSS) is a severe complication of inflammatory immune diseases
or treatment of malignancies; it may also appear during the progression of COVID-19. CSS …

The deregulated immune reaction and cytokines release storm (CRS) in COVID-19 disease

R Pasrija, M Naime - International Immunopharmacology, 2021 - Elsevier
COVID-19 caused by the SARS-CoV-2 virus, accompanies an unprecedented spike in
cytokines levels termed cytokines release syndrome (CRS), in critically ill patients. Clinicians …

COVID-19–associated collapsing glomerulopathy: an emerging entity

SH Nasr, JB Kopp - Kidney international reports, 2020 - kireports.org
Coronavirus disease 2019 (COVID-19) is an emerging human infectious disease caused by
a novel b coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach

G Morris, CC Bortolasci, BK Puri, L Olive, W Marx… - Life sciences, 2020 - Elsevier
In this paper, a model is proposed of the pathophysiological processes of COVID-19 starting
from the infection of human type II alveolar epithelial cells (pneumocytes) by SARS-CoV-2 …