Effect of systemic inflammation in the CNS: a silent history of neuronal damage

MV Millán Solano, C Salinas Lara… - International Journal of …, 2023 - mdpi.com
Central nervous system (CNS) infections including meningitis and encephalitis, resulting
from the blood-borne spread of specific microorganisms, provoke nervous tissue damage …

Immunopathogenesis of viral infections in neurological autoimmune disease

MA Habibi, F Nezhad Shamohammadi, T Rajaei… - BMC neurology, 2023 - Springer
Autoimmune diseases develop due to self-tolerance failure in recognizing self and non-self-
antigens. Several factors play a role in inducing autoimmunity, including genetic and …

Ubiquity of the SARS-CoV-2 receptor ACE2 and upregulation in limbic regions of Alzheimer's disease brain

Y Zhao, W Li, W Lukiw - Folia neuropathologica, 2021 - termedia.pl
The major route of entry for the severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) into human host cells is by means of the angiotensin-converting enzyme-2 (ACE2) …

PDZ-containing proteins targeted by the ACE2 receptor

C Caillet-Saguy, N Wolff - Viruses, 2021 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2) is a main receptor for SARS-CoV-2 entry to the
host cell. Indeed, the first step in viral entry is the binding of the viral trimeric spike (S) protein …

Parkinson's disease and SARS-CoV-2 infection: particularities of molecular and cellular mechanisms regarding pathogenesis and treatment

A Anghelescu, G Onose, C Popescu, M Băilă, SI Stoica… - Biomedicines, 2022 - mdpi.com
Accumulating data suggest that chronic neuroinflammation-mediated neurodegeneration is
a significant contributing factor for progressive neuronal and glial cell death in age-related …

Acquired agitation in acute respiratory distress syndrome with COVID-19 compared to influenza patients: a propensity score matching observational study

A Maamar, C Liard, W Doucet, F Reizine, B Painvin… - Virology Journal, 2022 - Springer
Background A growing body of evidence reports that agitation and encephalopathy are
frequent in critically ill Covid-19 patients. We aimed to assess agitation's incidence and risk …

[HTML][HTML] Anti-N-methyl-D-aspartate receptor encephalitis after coronavirus disease 2019: A case report and literature review

H Lee, JH Jeon, H Choi, SH Koh, KY Lee, YJ Lee… - Medicine, 2022 - journals.lww.com
Anti-N-methyl-D-aspartate receptor encephalitis after corona... : Medicine Anti-N-methyl-D-aspartate
receptor encephalitis after coronavirus disease 2019: A case report and literature review …

Prodrug therapies for infectious and neurodegenerative diseases

M Markovic, S Deodhar, J Machhi, P Yeapuri, M Saleh… - Pharmaceutics, 2022 - mdpi.com
Prodrugs are bioreversible drug derivatives which are metabolized into a pharmacologically
active drug following chemical or enzymatic modification. This approach is designed to …

Evaluation and treatment approaches for neurological post-acute sequelae of COVID-19: A consensus statement and scoping review from the global COVID-19 neuro …

JA Frontera, A Guekht, RF Allegri, M Ashraf… - Journal of the …, 2023 - Elsevier
Post-acute neurological sequelae of COVID-19 affect millions of people worldwide, yet little
data is available to guide treatment strategies for the most common symptoms. We …

COVID-19 and Alzheimer's Disease Share Common Neurological and Ophthalmological Manifestations: A Bidirectional Risk in the Post-Pandemic Future

G Amadoro, V Latina, E Stigliano, A Micera - Cells, 2023 - mdpi.com
A growing body of evidence indicates that a neuropathological cross-talk takes place
between the coronavirus disease 2019 (COVID-19)-the pandemic severe pneumonia that …