The contribution of endothelial cells to tissue fibrosis

E Romano, I Rosa, BS Fioretto… - Current Opinion in …, 2024 - journals.lww.com
An in-depth understanding of the mechanisms underlying EndMT or the acquisition of a
profibrotic secretory phenotype by endothelial cells will provide the rationale for novel …

[PDF][PDF] Idiopathic pulmonary fibrosis: where do we stand and how far to go

V Singh, I Ulasov, S Gupta, A Singh, VK Roy… - Discov …, 2024 - researchgate.net
Idiopathic pulmonary fibrosis is a progressive and incurable lung disease characterized by
collagen deposition, alveolar inflammation, fibroblast proliferation, and the destruction of …

Single cell meta-analysis of EndMT and EMT state in COVID-19

L Zhang, C Tang, M Zhang, X Tong, Y Xie… - Frontiers in …, 2022 - frontiersin.org
COVID-19 prognoses suggests that a proportion of patients develop fibrosis, but there is no
evidence to indicate whether patients have progression of mesenchymal transition (MT) in …

Vascular contribution to lung repair and fibrosis

N Caporarello, G Ligresti - American Journal of Respiratory Cell and …, 2023 - atsjournals.org
Lungs are constantly exposed to environmental perturbations and therefore have
remarkable capacity to regenerate in response to injury. Sustained lung injuries, aging, and …

Ginsenoside Rg3 attenuates pulmonary fibrosis by inhibiting endothelial to mesenchymal transition

E Yun, BS Kwon, J Kim, A Lee - Animal Cells and Systems, 2023 - Taylor & Francis
Pulmonary fibrosis (PF) is a progressive and chronic lung disease characterized by
excessive extracellular matrix (ECM) deposition and fibroblast proliferation. Endothelial-to …

Effects of hypoxia on bronchial and alveolar epithelial cells linked to pathogenesis in chronic lung disorders

R Berggren-Nylund, M Ryde, A Löfdahl… - Frontiers in …, 2023 - frontiersin.org
Introduction: Chronic lung disorders involve pathological alterations in the lung tissue with
hypoxia as a consequence. Hypoxia may influence the release of inflammatory mediators …

[HTML][HTML] Persistent alveolar type 2 dysfunction and lung structural derangement in post-acute COVID-19

AF Rendeiro, H Ravichandran, J Kim, AC Borczuk… - medRxiv, 2022 - ncbi.nlm.nih.gov
SARS-CoV-2 infection can manifest as a wide range of respiratory and systemic symptoms
well after the acute phase of infection in over 50% of patients. Key questions remain on the …

Reply: Transitioning endothelial cells contribute to pulmonary fibrosis

X Wu, KI Boström, Y Yao - European Respiratory Journal, 2023 - Eur Respiratory Soc
Extract We sincerely appreciate the correspondence from SS Sohal, whose recent
discoveries in human pulmonary fibrosis [1, 2] are complementary to our report on an …

Phenotypes of Sarcoidosis-Associated Pulmonary Hypertension—A Challenging Mystery

A Kacprzak, W Tomkowski, M Szturmowicz - Diagnostics, 2023 - mdpi.com
Sarcoidosis has been a well-recognised risk factor for pulmonary hypertension (PH) for a
long time, but still, the knowledge about this concatenation is incomplete. Sarcoidosis …

Endothelial to mesenchymal transition: a novel pathological feature of pulmonary fibrosis

SS Sohal - European Respiratory Journal, 2023 - Eur Respiratory Soc
Extract I read with great interest the recent original research article by Wu et al.[1] published
in the prestigious European Respiratory Journal (ERJ), which reported on endothelial cell …