Background & Aims Liver disease carries significant healthcare burden and frequently
requires a combination of blood tests, imaging, and invasive liver biopsy to diagnose …

Vasoconstrictors are the treatment of choice for hepatorenal syndrome (HRS). We evaluate
the real‐life effectiveness of a sequential vasoconstrictor regimen of midodrine–octreotide …

Alcohol-related hepatitis (ARH) is a unique type of alcohol-associated liver disease
characterized by acute liver inflammation caused by significant alcohol use. It ranges in …

Aims Infants with biliary atresia (BA) are treated with Kasai portoenterostomy (KPE) surgery,
but many BA patients need subsequent salvage liver transplants. The aim of this study is to …

Alcoholic hepatitis (AH) is a unique type of alcohol-associated liver disease (ALD)
characterized by acute liver inflammation caused by prolonged heavy alcohol use. The short …

Liver sinusoidal endothelial cells have a gatekeeper function in liver homeostasis by
permitting substrates from the bloodstream into the space of Disse and regulating hepatic …

The endoplasmic reticulum is a central player in liver pathophysiology. Chronic injury to the
ER through increased lipid content, alcohol metabolism, or accumulation of misfolded …

OBJECTIVES: Severe alcoholic hepatitis (sAH) confers substantial mortality, but the disease
course is difficult to predict. As iron parameters are attractive outcome predictors in other …

Alcoholic hepatitis is the severest clinical presentation of alcoholic liver disease. Lacking an
effective pharmacologic treatment, alcoholic hepatitis is associated with a poor prognosis …

Background Serum transferrin levels represent an independent predictor of mortality in
patients with liver failure. Hepatocyte nuclear factor 4 alpha (HNF4α) is a master regulator of …