Therapeutic strategies for COVID-19: progress and lessons learned

G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …

Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

Bioactive natural products in COVID-19 therapy

Z Wang, N Wang, L Yang, X Song - Frontiers in Pharmacology, 2022 - frontiersin.org
The devastating COVID-19 pandemic has caused more than six million deaths worldwide
during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic …

Chemical analysis of the Chinese herbal medicine licorice (Gan-Cao): An update review

Z Shang, C Liu, X Qiao, M Ye - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Licorice, called Gan-Cao in China, is one of the
most popular traditional herbal medicines. It is derived from the dried roots and rhizomes of …

[HTML][HTML] Schaftoside inhibits 3CLpro and PLpro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19

Y Yi, M Zhang, H Xue, R Yu, YO Bao, Y Kuang… - … Pharmaceutica Sinica B, 2022 - Elsevier
It is an urgent demand worldwide to control the coronavirus disease 2019 (COVID-19)
pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[HTML][HTML] Research progress of traditional Chinese medicine compound" Xiaochaihu Decoction" in the treatment of depression

C Sun, M Gao, M Qiao - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Depression is a common psychiatric disorder under the category of depression syndrome in
Traditional Chinese Medicine (TCM) theory. Meanwhile, Xiaochaihu Decoction is a classical …

Post-acute sequelae of SARS-CoV-2 infection: A neglected public health issue

Z Wang, L Yang - Frontiers in Public Health, 2022 - frontiersin.org
The COVID-19 pandemic has caused at least 508,827,830 infections and is associated with
a 1.2% mortality rate worldwide (1). New SARS-CoV-2 variants have driven new waves of …

A review of the antiviral activities of glycyrrhizic acid, glycyrrhetinic acid and glycyrrhetinic acid monoglucuronide

J Zuo, T Meng, Y Wang, W Tang - Pharmaceuticals, 2023 - mdpi.com
Licorice, a natural medicine derived from the roots and rhizomes of Glycyrrhiza species,
possesses a wide range of therapeutic applications, including antiviral properties …

Strategies for the management of spike protein-related pathology

MTJ Halma, C Plothe, P Marik, TA Lawrie - Microorganisms, 2023 - mdpi.com
In the wake of the COVID-19 crisis, a need has arisen to prevent and treat two related
conditions, COVID-19 vaccine injury and long COVID-19, both of which can trace at least …

Cheminformatics-based study identifies potential ebola VP40 inhibitors

E Broni, C Ashley, J Adams, H Manu, E Aikins… - International Journal of …, 2023 - mdpi.com
The Ebola virus (EBOV) is still highly infectious and causes severe hemorrhagic fevers in
primates. However, there are no regulatorily approved drugs against the Ebola virus disease …