Patients with heart failure (HF) syndromes have been categorized as those with reduced
ejection fraction (EF) or preserved EF (HFpEF), and ischemia plays a key role in both types …

Yellon, Derek M., and James M. Downey. Preconditioning the Myocardium: From Cellular
Physiology to Clinical Cardiology. Physiol Rev 83: 1113-1151, 2003; 10.1152/physrev …

MATERIALS AND METHODS Surgical preparation. The experimental animals were handled
in compliance with the Guiding Principles in the Use and Care of Animals published by the …

Practically any stimulus capable of causing injury to a tissue or organ can, when applied
close to (but below) the threshold of damage, activate endogenous protective mechanisms …

Among patients with HF or evidence of LV dysfunction after acute MI enrolled in the Optimal
Trial in Myocardial Infarction With the Angiotensin II Antagonist Losartan (OPTIMAAL) …

A brief period of cerebral ischemia confers transient tolerance to a subsequent ischemic
challenge in the brain. This phenomenon of ischemic tolerance has been confirmed in …

Oxygen is essential for living organisms. Molecular oxygen binds to hemoglobin and is
delivered to every organ in the body. In several cardiovascular diseases or anemia, local …

There is increasing evidence that physical activity is associated with a decreased stroke risk.
The purpose of this study was to determine if exercise could also reduce brain damage in …

The purpose of this study was to determine if exercise could induce expression of vascular
endothelial growth factor (VEGF) and angiopoietin 1 and 2, in association with …

The effect that exercise has on angiogenesis in the aging rat is unknown. We initiated this
study with the intent to determine if exercise could induce angiogenesis in aging rats, as well …