[HTML][HTML] Laboratory biomarkers for diagnosis and prognosis in COVID-19

D Battaglini, M Lopes-Pacheco… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes a wide spectrum of
clinical manifestations, with progression to multiorgan failure in the most severe cases …

COVIDomics: The proteomic and metabolomic signatures of COVID-19

M Costanzo, M Caterino, R Fedele, A Cevenini… - International journal of …, 2022 - mdpi.com
Omics-based technologies have been largely adopted during this unprecedented global
COVID-19 pandemic, allowing the scientific community to perform research on a large scale …

Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19

S Druzak, E Iffrig, BR Roberts, T Zhang… - Nature …, 2023 - nature.com
The pathogenesis of multi-organ dysfunction associated with severe acute SARS-CoV-2
infection remains poorly understood. Endothelial damage and microvascular thrombosis …

Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision medicine

A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …

Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models

Y Jiang, Y Deng, H Pang, T Ma, Q Ye, Q Chen, H Chen… - Cell Discovery, 2022 - nature.com
The global COVID-19 epidemic has spread rapidly around the world and caused the death
of more than 5 million people. It is urgent to develop effective strategies to treat COVID-19 …

[HTML][HTML] Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19

C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …

Metabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation

FC Ceballos, A Virseda-Berdices, S Resino… - Frontiers in …, 2022 - frontiersin.org
Background metabolic changes through SARS-CoV-2 infection has been reported but not
fully comprehended. This metabolic dysregulation affects multiple organs during COVID-19 …

COVID-19 and one-carbon metabolism

J Perła-Kaján, H Jakubowski - International journal of molecular sciences, 2022 - mdpi.com
Dysregulation of one-carbon metabolism affects a wide range of biological processes and is
associated with a number of diseases, including cardiovascular disease, dementia, neural …

Rapidity and precision of steroid hormone measurement

S Karashima, I Osaka - Journal of Clinical Medicine, 2022 - mdpi.com
Steroids are present in all animals and plants, from mammals to prokaryotes. In the medical
field, steroids are commonly classified as glucocorticoids, mineralocorticoids, and gonadal …

Metabolomics Approaches for the Diagnosis, Treatment, and Better Disease Management of Viral Infections

H Al-Sulaiti, J Almaliti, CB Naman, AA Al Thani… - Metabolites, 2023 - mdpi.com
Metabolomics is an analytical approach that involves profiling and comparing the
metabolites present in biological samples. This scoping review article offers an overview of …