[HTML][HTML] Repurposing of drugs for combined treatment of COVID-19 cytokine storm using machine learning
MR Gantla, IF Tsigelny, VL Kouznetsova - Medicine in Drug Discovery, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) induced cytokine storm is
the major cause of COVID-19 related deaths. Patients have been treated with drugs that …
the major cause of COVID-19 related deaths. Patients have been treated with drugs that …
Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity
Comparing SARS-CoV-2 infection-induced gene expression signatures to drug treatment-
induced gene expression signatures is a promising bioinformatic tool to repurpose existing …
induced gene expression signatures is a promising bioinformatic tool to repurpose existing …
COVID-19 induces cytokine storm and dysfunctional hemostasis
J Charles, VA Ploplis - Current Drug Targets, 2022 - ingentaconnect.com
Background: Infection with SARS-CoV-2 leads to COVID-19 which can manifest in various
ways from asymptomatic or mild disease to acute respiratory distress syndrome. The …
ways from asymptomatic or mild disease to acute respiratory distress syndrome. The …
Could aquaporin modulators be employed as prospective drugs for COVID-19 related pulmonary comorbidity?
LF Mariajoseph-Antony, A Kannan… - Medical …, 2020 - Elsevier
COVID-19 initially an epidemic caused by SARS-CoV-2 has turned out to be a life-
threatening global pandemic with increased morbidity and mortality. The presence of …
threatening global pandemic with increased morbidity and mortality. The presence of …
[HTML][HTML] Comparison of C-reactive protein and C-reactive protein-to-albumin ratio in predicting mortality among geriatric coronavirus disease 2019 patients
SUMMARY OBJECTIVE: The aim of this study was to evaluate and compare C-reactive
protein and C-reactive protein-to-albumin ratio performances in predicting mortality of …
protein and C-reactive protein-to-albumin ratio performances in predicting mortality of …
Human Identical Sequences, hyaluronan, and hymecromone─ the new mechanism and management of COVID-19
S Yang, Y Tong, L Chen, W Yu - Molecular Biomedicine, 2022 - Springer
COVID-19 caused by SARS-CoV-2 has created formidable damage to public health and
market economy. Currently, SARS-CoV-2 variants has exacerbated the transmission from …
market economy. Currently, SARS-CoV-2 variants has exacerbated the transmission from …
Immunomodulatory potential of bioactive compounds of betel leaf extract targeting COVID-19 immunological human host proteins: An in silico study
MJ Kalalo, SB Simanjuntak, TA Hebber… - Journal of Applied …, 2022 - japsonline.com
Forests contain nearly all of the natural resources required by humans. Apart from food, the
community makes use of forest products for medicinal purposes. Betel (Piper betle L.) is one …
community makes use of forest products for medicinal purposes. Betel (Piper betle L.) is one …
Epithelial MAPK signaling directs endothelial NRF2 signaling and IL-8 secretion in a tri-culture model of the alveolar-microvascular interface following diesel exhaust …
ECM Vitucci, AE Simmons, EM Martin… - Particle and Fibre …, 2024 - Springer
Abstract Background Particulate matter 2.5 (PM2. 5) deposition in the lung's alveolar
capillary region (ACR) is significantly associated with respiratory disease development, yet …
capillary region (ACR) is significantly associated with respiratory disease development, yet …
Effect of COVID-19 pandemic on patients who have undergone liver transplantation because of hepatocellular carcinoma
Abstract Background and Aim Many clinical studies have shown that the COVID-19 case
fatality rate is higher in older patients, those with comorbidities, those with …
fatality rate is higher in older patients, those with comorbidities, those with …
[HTML][HTML] The effect on the immune system in the human body due to COVID-19: an insight on traditional to modern approach as a preventive measure
J Sutradhar, BR Sarkar - Journal of pharmacopuncture, 2021 - ncbi.nlm.nih.gov
The COVID-19, the most infectious pandemic disease arising due to SARS-CoV-2 (Severe
Acute Respiratory Syndrome Coronavirus 2) has caused huge issues globally. In this …
Acute Respiratory Syndrome Coronavirus 2) has caused huge issues globally. In this …