Natural and experimental SARS-CoV-2 infection in domestic and wild animals
DA Meekins, NN Gaudreault, JA Richt - Viruses, 2021 - mdpi.com
SARS-CoV-2 is the etiological agent responsible for the ongoing COVID-19 pandemic,
which continues to spread with devastating effects on global health and socioeconomics …
which continues to spread with devastating effects on global health and socioeconomics …
An overview of SARS-CoV-2 and animal infection
A novel coronavirus has been reported as the causative pathogen of the Coronavirus
disease 2019 (COVID-19) outbreak in Wuhan city, China in December 2019. Due to the …
disease 2019 (COVID-19) outbreak in Wuhan city, China in December 2019. Due to the …
[HTML][HTML] Endothelial cell infection and dysfunction, immune activation in severe COVID-19
Rationale: Pulmonary vascular endotheliitis, perivascular inflammation, and immune
activation are observed in COVID-19 patients. While the initial SARS-CoV-2 infection mainly …
activation are observed in COVID-19 patients. While the initial SARS-CoV-2 infection mainly …
On-site airborne pathogen detection for infection risk mitigation
Human-infecting pathogens that transmit through the air pose a significant threat to public
health. As a prominent instance, the severe acute respiratory syndrome coronavirus 2 …
health. As a prominent instance, the severe acute respiratory syndrome coronavirus 2 …
[HTML][HTML] Susceptibility of pets to SARS-CoV-2 infection: lessons from a seroepidemiologic survey of cats and dogs in Portugal
R Barroso, A Vieira-Pires, A Antunes… - Microorganisms, 2022 - mdpi.com
Betacoronavirus (β-CoV) are positive single-stranded RNA viruses known to infect
mammals. In 2019, a novel zoonotic β-CoV emerged, the severe acute respiratory syndrome …
mammals. In 2019, a novel zoonotic β-CoV emerged, the severe acute respiratory syndrome …
SARS-CoV-2 brain regional detection, histopathology, gene expression, and immunomodulatory changes in decedents with COVID-19
GE Serrano, JE Walker, C Tremblay… - … of Neuropathology & …, 2022 - academic.oup.com
Brains of 42 COVID-19 decedents and 107 non-COVID-19 controls were studied. RT-PCR
screening of 16 regions from 20 COVID-19 autopsies found SARS-CoV-2 E gene viral …
screening of 16 regions from 20 COVID-19 autopsies found SARS-CoV-2 E gene viral …
Intranasal type I interferon treatment is beneficial only when administered before clinical signs onset in the SARS-CoV-2 hamster model
P Bessière, M Wasniewski, E Picard-Meyer… - PLoS …, 2021 - journals.plos.org
Impaired type I interferons (IFNs) production or signaling have been associated with severe
COVID-19, further promoting the evaluation of recombinant type I IFNs as therapeutics …
COVID-19, further promoting the evaluation of recombinant type I IFNs as therapeutics …
Development of an inactivated vaccine against SARS CoV-2
The rapid spread of SARS-CoV-2 with its mutating strains has posed a global threat to safety
during this COVID-19 pandemic. Thus far, there are 123 candidate vaccines in human …
during this COVID-19 pandemic. Thus far, there are 123 candidate vaccines in human …
Ferrets are valuable models for SARS-CoV-2 research
M Ciurkiewicz, F Armando, T Schreiner… - Veterinary …, 2022 - journals.sagepub.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), resulted in an ongoing pandemic with millions of deaths …
coronavirus 2 (SARS-CoV-2), resulted in an ongoing pandemic with millions of deaths …
SARS-CoV-2 infection dysregulates cilia and basal cell homeostasis in the respiratory epithelium of hamsters
T Schreiner, L Allnoch, G Beythien, K Marek… - International journal of …, 2022 - mdpi.com
Similar to many other respiratory viruses, SARS-CoV-2 targets the ciliated cells of the
respiratory epithelium and compromises mucociliary clearance, thereby facilitating spread to …
respiratory epithelium and compromises mucociliary clearance, thereby facilitating spread to …