Epigenetic clock and methylation studies in elephants

NA Prado, JL Brown, JA Zoller, A Haghani, M Yao… - Aging cell, 2021 - Wiley Online Library
Age‐associated DNA‐methylation profiles have been used successfully to develop highly
accurate biomarkers of age (" epigenetic clocks") in humans, mice, dogs, and other species …

A review of mechanistic models of viral dynamics in bat reservoirs for zoonotic disease

AD Gentles, S Guth, C Rozins… - Pathogens and global …, 2020 - Taylor & Francis
The emergence of SARS-CoV-2, a coronavirus with suspected bat origins, highlights a
critical need for heightened understanding of the mechanisms by which bats maintain …

DNA methylation networks underlying mammalian traits

A Haghani, CZ Li, TR Robeck, J Zhang, AT Lu… - Science, 2023 - science.org
Using DNA methylation profiles (n= 15,456) from 348 mammalian species, we constructed
phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using …

Epigenetic predictors of maximum lifespan and other life history traits in mammals

CZ Li, A Haghani, TR Robeck, D Villar, AT Lu, J Zhang… - BioRxiv, 2021 - biorxiv.org
Maximum lifespan of a species is the oldest that individuals can survive, reflecting the
genetic limit of longevity in an ideal environment. Here we report methylation-based models …

Comparing age‐and bone‐related differences in collagen fiber orientation: A case study of bats and laboratory mice using quantitative polarized light microscopy

TL Hieronymus, DA Waugh, HC Ball… - The Anatomical …, 2024 - Wiley Online Library
As bones age in most mammals, they typically become more fragile. This state of bone
fragility is often associated with more homogenous collagen fiber orientations (CFO). Unlike …

Penguins, falcons, and mountain lions: the extraordinary host diversity of vampire bats

G Carter, B Brown, I Razik, S Ripperger - 50 years of bat research …, 2021 - Springer
Common vampire bats (Desmodus rotundus), white-winged vampire bats (Diaemus youngi),
and hairy-legged vampire bats (Diphylla ecaudata) are the only obligate blood-feeding …

Mercury concentrations decline with age in the fur of females of an insectivorous terrestrial mammal (Myotis lucifugus)

AD Grottoli, HK Swanson, HG Broders - Science of The Total Environment, 2023 - Elsevier
Methylmercury (MeHg) is a toxic form of mercury that bioaccumulates in organisms and
biomagnifies through food webs. MeHg concentrations can be high in aquatic environments …

[PDF][PDF] A review of mechanistic models of viral dynamics in bat reservoirs for zoonotic

AD Gentles, S Guth, C Rozins, CE Brook - 2020 - scienceopen.com
The emergence of SARS-CoV-2, a coronavirus with suspected bat origins, highlights a
critical need for heightened understanding of the mechanisms by which bats maintain …