Pathogenesis of bronchopulmonary dysplasia: role of oxidative stress from 'Omics' studies

A Kimble, ME Robbins, M Perez - Antioxidants, 2022 - mdpi.com
Bronchopulmonary dysplasia (BPD) remains the most common respiratory complication of
prematurity as younger and smaller infants are surviving beyond the immediate neonatal …

Epigenetic modifications in the development of bronchopulmonary dysplasia: a review

L Wang, J Xiao, B Zhang, A Hou - Pediatric Research, 2024 - nature.com
While perinatal medicine advancements have bolstered survival outcomes for premature
infants, bronchopulmonary dysplasia (BPD) continues to threaten their long-term health …

Analysis of neonatal neurobehavior and developmental outcomes among preterm infants

EC McGowan, JA Hofheimer, TM O'Shea… - JAMA Network …, 2022 - jamanetwork.com
Importance The ability to identify poor outcomes and treatable risk factors among very
preterm infants remains challenging; improving early risk detection and intervention targets …

Prospective epigenome and transcriptome analyses of cord and peripheral blood from preterm infants at risk of bronchopulmonary dysplasia

HY Cho, X Wang, MR Campbell, V Panduri… - Scientific Reports, 2023 - nature.com
Bronchopulmonary dysplasia (BPD) is a prevalent chronic lung disease of prematurity with
limited treatment options. To uncover biomarkers of BPD risk, this study investigated …

Association of pediatric buccal epigenetic age acceleration with adverse neonatal brain growth and neurodevelopmental outcomes among children born very preterm …

N Gomaa, C Konwar, N Gladish… - JAMA network …, 2022 - jamanetwork.com
Importance Very preterm neonates (24-32 weeks' gestation) remain at a higher risk of
morbidity and neurodevelopmental adversity throughout their lifespan. Because the extent of …

Epigenome-wide association study of bronchopulmonary dysplasia in preterm infants: results from the discovery-BPD program

X Wang, HY Cho, MR Campbell, V Panduri… - Clinical …, 2022 - Springer
Background Bronchopulmonary dysplasia (BPD) is a lung disease in premature infants
caused by therapeutic oxygen supplemental and characterized by impaired pulmonary …

[HTML][HTML] Immuno-epigenetic signature derived in saliva associates with the encephalopathy of prematurity and perinatal inflammatory disorders

ELS Conole, K Vaher, MB Cabez, G Sullivan… - Brain, Behavior, and …, 2023 - Elsevier
Background Preterm birth is closely associated with a phenotype that includes brain
dysmaturation and neurocognitive impairment, commonly termed Encephalopathy of …

Environmental influences on child health outcomes: cohorts of individuals born very preterm

TM O'Shea, M McGrath, JL Aschner, B Lester… - Pediatric …, 2023 - nature.com
Abstract The National Institutes of Health's Environmental influences on Child Health
Outcomes (ECHO) Program was designed to address solution-oriented research questions …

Epigenetic associations in HPA axis genes related to bronchopulmonary dysplasia and antenatal steroids

KM Hodge, V Zhabotynsky, AA Burt, BS Carter… - Pediatric …, 2024 - nature.com
Background Bronchopulmonary dysplasia (BPD), a common morbidity among very preterm
infants, is associated with chronic disease and neurodevelopmental impairments. A …

DNA methylation in relation to gestational age and brain dysmaturation in preterm infants

ENW Wheater, P Galdi, DL McCartney… - Brain …, 2022 - academic.oup.com
Preterm birth is associated with dysconnectivity of structural brain networks and is a leading
cause of neurocognitive impairment in childhood. Variation in DNA methylation is …