[HTML][HTML] Ocular drug delivery: a comprehensive review

S Ahmed, MM Amin, S Sayed - AAPS PharmSciTech, 2023 - Springer
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

[HTML][HTML] Current trends in pharmaceutical treatment of dry eye disease: A review

HB Mohamed, BN Abd El-Hamid, D Fathalla… - European Journal of …, 2022 - Elsevier
Dry eye disease (DED), keratoconjunctivitis sicca or dysfunctional tear syndrome, is the most
prevalent ophthalmic disease which affects a substantial segment of people worldwide with …

Bibliometric and visualized analysis of ocular drug delivery from 2001 to 2020

C Peng, L Kuang, J Zhao, AE Ross, Z Wang… - Journal of Controlled …, 2022 - Elsevier
Objective To perform a bibliometric analysis in the field of ocular drug delivery research to
characterize the current international trends and to present visual representations of the past …

[HTML][HTML] Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

[HTML][HTML] Lipid nanoparticles as a promising drug delivery carrier for topical ocular therapy—an overview on recent advances

S Jacob, AB Nair, J Shah, S Gupta, SHS Boddu… - Pharmaceutics, 2022 - mdpi.com
Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …

Hydrogels-based ophthalmic drug delivery systems for treatment of ocular diseases

G Fang, X Yang, Q Wang, A Zhang, B Tang - Materials Science and …, 2021 - Elsevier
An increasing number of people worldwide are affected by eye diseases, eventually leading
to visual impairment or complete blindness. Conventional treatment involves the use of eye …

Ophthalmic nanoemulsions: From composition to technological processes and quality control

A Gawin-Mikołajewicz, KP Nartowski… - Molecular …, 2021 - ACS Publications
Nanoemulsions are considered as the most promising solution to improve the delivery of
ophthalmic drugs. The design of ophthalmic nanoemulsions requires an extensive …

Nanoemulsion delivery systems for enhanced efficacy of antimicrobials and essential oils

CR Garcia, MH Malik, S Biswas, VH Tam… - Biomaterials …, 2022 - pubs.rsc.org
The ever-growing threat of new and existing infectious diseases in combination with
antimicrobial resistance requires the need for innovative and effective forms of drug delivery …

An insight on ophthalmic drug delivery systems: focus on polymeric biomaterials-based carriers

M Shafiq, M Rafique, Y Cui, L Pan, CW Do… - Journal of Controlled …, 2023 - Elsevier
Presently, different types of eye diseases, such as glaucoma, myopia, infection, and dry eyes
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …

Oxygen self-supplying nanotherapeutic for mitigation of tissue hypoxia and enhanced photodynamic therapy of bacterial keratitis

Y Bai, Y Hu, Y Gao, X Wei, J Li, Y Zhang… - … Applied Materials & …, 2021 - ACS Publications
Hypoxia, a common characteristic of bacterial infections, is known to be closely associated
with the emergence of multidrug-resistant bacteria, which hastens the need to develop …