Aims/hypothesis The aim of this work was to examine the relationship between family history
of type 1 diabetes, birthweight, growth during the first 2 years and development of multiple …

Type 1 diabetes can be diagnosed at any age, but the incidence rate is highest in
adolescence, and most available data on risk factors are on children and adolescents. The …

GAD-alum given into lymph nodes to Type 1 diabetes (T1D) patients participating in a
multicenter, randomized, placebo-controlled double-blind study seemed to have a positive …

Autoimmune diseases occur when the body's natural defense system fails to differentiate its
own cells from the foreign cells and mistakenly attacks the healthy cells. Among the …

Our aim was to investigate the associations between erythrocyte fatty acids and the risk of
islet autoimmunity in children. The Environmental Determinants of Diabetes in the Young …

Aims/hypothesis We studied the association of plasma ascorbic acid with the risk of
developing islet autoimmunity and type 1 diabetes and examined whether SNPs in vitamin …

Objective Type 1 diabetes (T1D) progression is affected by circulating glutamic acid
decarboxylase antibody (GADA) that persist for many years. This study aimed at …

The autoimmune pathogenesis of type 1 diabetes (T1D) involves cellular infiltration from
innate and adaptive immune subsets into the islets of Langerhans within the pancreas; …

A declining first-phase insulin response (FPIR) is associated with positivity for multiple islet
autoantibodies, irrespective of class II HLA DR-DQ genotype. We examined the associations …

HLA-DQA1 and-DQB1 are strongly associated with type 1 diabetes (T1D), and DQ8. 1 and
DQ2. 5 are major risk haplotypes. Next-generation targeted sequencing of HLA-DQA1 and …