Antioxidant activity and polyphenol and procyanidin contents of selected commercially available cocoa-containing and chocolate products in the United States

KB Miller, DA Stuart, NL Smith, CY Lee… - Journal of agricultural …, 2006 - ACS Publications
In the United States, commercially available foods, including cocoa and chocolate, are being
marketed with statements referring to the level of antioxidant activity and polyphenols. For …

Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt …

M Gómez-Guzmán, R Jiménez, M Sánchez… - Free Radical Biology …, 2012 - Elsevier
Flavanol-rich diets have been reported to exert beneficial effects in preventing
cardiovascular diseases, such as hypertension. We studied the effects of chronic treatment …

Plant polyphenols: how to translate their in vitro antioxidant actions to in vivo conditions

CG Fraga - IUBMB life, 2007 - Wiley Online Library
Epidemiological evidence demonstrates that diets rich in fruit and vegetables promote
health, and attenuate, or delay, the onset of various diseases, including cardiovascular …

Natural antioxidants and hypertension: promise and challenges

TJ Kizhakekuttu, ME Widlansky - Cardiovascular therapeutics, 2010 - Wiley Online Library
Hypertension reigns as a leading cause of cardiovascular morbidity and mortality worldwide.
Excessive reactive oxygen species (ROS) have emerged as a central common pathway by …

Effects of cocoa products/dark chocolate on serum lipids: a meta-analysis

OA Tokede, JM Gaziano, L Djousse - European journal of clinical …, 2011 - nature.com
Cocoa products, which are rich sources of flavonoids, have been shown to reduce blood
pressure and the risk of cardiovascular disease. Dark chocolate contains saturated fat and is …

The metabolic syndrome: definition, global impact, and pathophysiology

MV Potenza, JI Mechanick - Nutrition in Clinical Practice, 2009 - Wiley Online Library
The metabolic syndrome (MS) is a cluster of metabolic derangements that are associated
with primary disturbances in adipose tissue. Abnormal visceral fat accumulates from …

Flavonoids, vascular function and cardiovascular protection

D Grassi, G Desideri, G Croce, S Tiberti… - Current …, 2009 - ingentaconnect.com
A large body of evidence supports that the dietary intake of polyphenols-particularly of
flavonoids and the specific class of flavonoids named flavanols-might be able to exert some …

[HTML][HTML] Targeting inflammation by flavonoids: novel therapeutic strategy for metabolic disorders

MH Farzaei, AK Singh, R Kumar, CR Croley… - International journal of …, 2019 - mdpi.com
A balanced metabolic profile is essential for normal human physiological activities.
Disproportions in nutrition give rise to imbalances in metabolism that are associated with …

Vascular action of polyphenols

D Ghosh, A Scheepens - Molecular nutrition & food research, 2009 - Wiley Online Library
Dietary patterns are widely recognised as contributors to cardiovascular and
cerebrovascular disease. Endothelial function, the elastic properties of large arteries and the …

Effect of cocoa flavanols and exercise on cardiometabolic risk factors in overweight and obese subjects

K Davison, AM Coates, JD Buckley… - International journal of …, 2008 - nature.com
Objective: Impaired endothelial function in obesity may reduce blood flow to sites of
metabolism, contributing to impaired fat oxidation and insulin resistance. This study …