[HTML][HTML] The role and activity of SWI/SNF chromatin remodelers

T Bieluszewski, S Prakash, T Roulé… - Annual Review of Plant …, 2023 - annualreviews.org
SWITCH deficient SUCROSE NONFERMENTING (SWI/SNF) class chromatin remodeling
complexes (CRCs) use the energy derived from ATP hydrolysis to facilitate access of …

[HTML][HTML] The BAF chromatin remodeler synergizes with RNA polymerase II and transcription factors to evict nucleosomes

S Brahma, S Henikoff - Nature genetics, 2024 - nature.com
Chromatin accessibility is a hallmark of active transcription and entails ATP-dependent
nucleosome remodeling, which is carried out by complexes such as Brahma-associated …

ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis

D Barisic, CR Chin, C Meydan, M Teater, I Tsialta… - Cancer cell, 2024 - cell.com
ARID1A, a subunit of the canonical BAF nucleosome remodeling complex, is commonly
mutated in lymphomas. We show that ARID1A orchestrates B cell fate during the germinal …

Canonical BAF complex activity shapes the enhancer landscape that licenses CD8+ T cell effector and memory fates

B McDonald, BY Chick, NS Ahmed, M Burns, S Ma… - Immunity, 2023 - cell.com
CD8+ T cells provide host protection against pathogens by differentiating into distinct
effector and memory cell subsets, but how chromatin is site-specifically remodeled during …

Global identification of SWI/SNF targets reveals compensation by EP400

BJE Martin, EF Ablondi, C Goglia, CA Mimoso… - Cell, 2023 - cell.com
Mammalian SWI/SNF chromatin remodeling complexes move and evict nucleosomes at
gene promoters and enhancers to modulate DNA access. Although SWI/SNF subunits are …

RNA polymerase II promotes the organization of chromatin following DNA replication

S Bandau, V Alvarez, H Jiang, S Graff… - EMBO …, 2024 - embopress.org
Understanding how chromatin organisation is duplicated on the two daughter strands is a
central question in epigenetics. In mammals, following the passage of the replisome …

[HTML][HTML] The SWI/SNF ATP-dependent chromatin remodeling complex in cell lineage priming and early development

D Saha, S Animireddy… - Biochemical Society …, 2024 - portlandpress.com
ATP dependent chromatin remodelers have pivotal roles in transcription, DNA replication
and repair, and maintaining genome integrity. SWI/SNF remodelers were first discovered in …

[HTML][HTML] The esBAF and ISWI nucleosome remodeling complexes influence occupancy of overlapping dinucleosomes and fragile nucleosomes in murine embryonic …

DC Klein, K Troy, SA Tripplehorn, SJ Hainer - BMC genomics, 2023 - Springer
Background Nucleosome remodeling factors regulate the occupancy and positioning of
nucleosomes genome-wide through ATP-driven DNA translocation. While many …

[HTML][HTML] SWI/SNF-dependent genes are defined by their chromatin landscape

L Basurto-Cayuela, JA Guerrero-Martínez… - Cell Reports, 2024 - cell.com
SWI/SNF complexes are evolutionarily conserved, ATP-dependent chromatin remodeling
machines. Here, we characterize the features of SWI/SNF-dependent genes using BRM014 …

[HTML][HTML] Zinc deficiency is associated with the development of ovarian endometrial cysts

T Onuma, T Mizutani, Y Fujita, N Ohgami… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Ovarian cancers derived from endometrial cysts, also known as endometriosis in ovaries,
are widespread histological types in Japan. Several studies suggest that zinc deficiency …