Risk and protective factors for COVID-19 morbidity, severity, and mortality

J Zhang, X Dong, G Liu, Y Gao - Clinical reviews in allergy & immunology, 2023 - Springer
The outbreak of the coronavirus disease 2019 (COVID-19), caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become an evolving global …

Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension

B Zhou, P Perel, GA Mensah, M Ezzati - Nature Reviews Cardiology, 2021 - nature.com
High blood pressure is one of the most important risk factors for ischaemic heart disease,
stroke, other cardiovascular diseases, chronic kidney disease and dementia. Mean blood …

Oral nirmatrelvir for high-risk, nonhospitalized adults with Covid-19

J Hammond, H Leister-Tebbe, A Gardner… - … England Journal of …, 2022 - Mass Medical Soc
Background Nirmatrelvir is an orally administered severe acute respiratory syndrome
coronavirus 2 main protease (Mpro) inhibitor with potent pan–human-coronavirus activity in …

SARS-CoV-2, COVID-19 and the aging immune system

JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …

Female sex is a risk factor associated with long-term post-COVID related-symptoms but not with COVID-19 symptoms: the LONG-COVID-EXP-CM multicenter study

C Fernández-de-Las-Peñas… - Journal of clinical …, 2022 - mdpi.com
This multicenter cohort study investigated the differences between coronavirus disease
2019 (COVID-19) related symptoms and post-COVID symptoms between male and female …

Inflammasome activation at the crux of severe COVID-19

SM Vora, J Lieberman, H Wu - Nature Reviews Immunology, 2021 - nature.com
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), results in life-threatening disease in a minority of patients, especially elderly …

Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

Population risk factors for severe disease and mortality in COVID-19: A global systematic review and meta-analysis

A Booth, AB Reed, S Ponzo, A Yassaee, M Aral… - PloS one, 2021 - journals.plos.org
Aim COVID-19 clinical presentation is heterogeneous, ranging from asymptomatic to severe
cases. While there are a number of early publications relating to risk factors for COVID-19 …

From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human coronaviruses

Z Zhu, X Lian, X Su, W Wu, GA Marraro, Y Zeng - Respiratory research, 2020 - Springer
Within two decades, there have emerged three highly pathogenic and deadly human
coronaviruses, namely SARS-CoV, MERS-CoV and SARS-CoV-2. The economic burden …

Causal relationship between physical activity, leisure sedentary behaviors and COVID-19 risk: a Mendelian randomization study

X Chen, X Hong, W Gao, S Luo, J Cai, G Liu… - Journal of translational …, 2022 - Springer
Background The 2019 coronavirus disease pandemic (COVID-19) poses an enormous
threat to public health worldwide, and the ensuing management of social isolation has …