[HTML][HTML] Role of ROCK signaling in virus replication
Rho-associated protein kinase (ROCK) is a serine-threonine kinase and is a major
downstream effector of the small GTPaseRhoA. Upon activation, Rho/ROCK cell signaling …
downstream effector of the small GTPaseRhoA. Upon activation, Rho/ROCK cell signaling …
Discovery of Pyrano[2,3-c]pyrazole Derivatives as Novel Potential Human Coronavirus Inhibitors: Design, Synthesis, In Silico, In Vitro, and ADME Studies
The SARS-CoV-2 pandemic at the end of 2019 had major worldwide health and economic
consequences. Until effective vaccination approaches were created, the healthcare sectors …
consequences. Until effective vaccination approaches were created, the healthcare sectors …
Pelargonium sidoides Root Extract: Simultaneous HPLC Separation, Determination, and Validation of Selected Biomolecules and Evaluation of SARS-CoV-2 …
This study aimed to establish a validated HPLC-UV analytical method for the determination
of gallic acid, catechin, scopoletin, and umckalin in phytoformulations containing P. sidoides …
of gallic acid, catechin, scopoletin, and umckalin in phytoformulations containing P. sidoides …
Antiviral activity of Humulus lupulus (HOP) aqueous extract against MERS-CoV and SARS-CoV-2: in-vitro and in-silico study
TA Bouback, AM Aljohani, A Albeshri… - Biotechnology & …, 2023 - Taylor & Francis
Coronaviruses emerged three times in the last two decades and became a source of
concern globally. Humulus lupulus plant has been used widely in medical science. Our …
concern globally. Humulus lupulus plant has been used widely in medical science. Our …
Discovery of novel thioquinazoline-N-aryl-acetamide/N-arylacetohydrazide hybrids as anti-SARS-CoV-2 agents: Synthesis, in vitro biological evaluation, and …
HT Abdel-Mohsen, MA Omar, O Kutkat… - Journal of Molecular …, 2023 - Elsevier
In the current investigation, two novel series of (tetrahydro) thioquinazoline-N-
arylacetamides and (tetrahydro) thioquinazoline-N-arylacetohydrazides were designed …
arylacetamides and (tetrahydro) thioquinazoline-N-arylacetohydrazides were designed …
Synthesis of 5-heptadecyl-4H-1, 2, 4-triazole incorporated indole moiety: Antiviral (SARS-CoV-2), antimicrobial, and molecular docking studies
HA Abd El Salam, HM Abo-Salem, O Kutkat… - Journal of Molecular …, 2024 - Elsevier
Two series of Schiff bases and Mannich bases derived from 5-heptadecyl-4H-1, 2, 4-triazole
hybrids of indole moiety have been synthesized. First, the acid-catalyzed reaction of N …
hybrids of indole moiety have been synthesized. First, the acid-catalyzed reaction of N …
Iterated virtual screening-assisted antiviral and enzyme inhibition assays reveal the discovery of novel promising anti-SARS-CoV-2 with dual activity
Unfortunately, COVID-19 is still a threat to humankind and has a dramatic impact on human
health, social life, the world economy, and food security. With the limited number of …
health, social life, the world economy, and food security. With the limited number of …
Antibacterial and anti-corona virus (229E) activity of Nigella sativa oil combined with photodynamic therapy based on methylene blue in wound infection: in vitro and …
SE Abo-Neima, MM El-Sheekh, MI Al-Zaban… - BMC microbiology, 2023 - Springer
Microbial skin infections, antibiotic resistance, and poor wound healing are major problems,
and new treatments are needed. Our study targeted solving this problem with Nigella sativa …
and new treatments are needed. Our study targeted solving this problem with Nigella sativa …
[HTML][HTML] The role of turmeric and black pepper oil nanoemulsion in attenuating cytokine storm triggered by duck hepatitis A virus type I (DHAV-I)-induced infection in …
HS El-Sayed, AS Saad, WA Tawfik, A Adel… - Poultry science, 2024 - Elsevier
The cytokine storm induced by duck hepatitis A virus type 1 (DHAV-1) infection significantly
contributes to severe, rapid deaths and economic losses in the duck industry in Egypt. This …
contributes to severe, rapid deaths and economic losses in the duck industry in Egypt. This …
Formulation and in vitro characterization of nanoemulsions containing remdesivir or licorice extract: A potential subcutaneous injection for coronavirus treatment
G Al Zahraa, GF Balata - Colloids and Surfaces B: Biointerfaces, 2024 - Elsevier
The management of coronavirus necessitates that medicines are available, reasonably
priced, and easy to administer. The work aimed at formulating and characterizing remdesivir …
priced, and easy to administer. The work aimed at formulating and characterizing remdesivir …