Background To address the emergence of SARS-CoV-2, multiple clinical trials in humans
were rapidly started, including those involving an oral treatment by nitazoxanide, despite no …

The SARS‐CoV‐2 Omicron variant has spread rapidly and is considered the predominant
variant in the world, and its main characteristic is related to evade immunity from natural …

Host cell invasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
mediated by the interaction of the viral spike protein (S) with human angiotensin-converting …

We have discovered a family of synthetic oxazole-based macrocycles to be active against
SARS-CoV-2. The synthesis, pharmacological properties, and docking studies of the …

This paper describes an inclusive biophysical study elucidating the interaction of therapeutic
drug azithromycin (Azith) with hen egg white lysozyme (HEWL). Spectroscopic and …

Chlorpheniramine Maleate (CPM), also known as chlorphenamine, is a potent alkylamine
first-generation H1 antihistamine that has been used since the 1950s. CPM is a widely …

The outbreak of the COVID-19 pandemic in China has become an urgent health and
economic challenge. There is a current race for developing strategies to treat and/or prevent …

Researchers worldwide are looking for molecules that might disrupt the COVID-19 life cycle.
Endoribonuclease, which is responsible for processing viral RNA to avoid detection by the …

Background One of the most dangerous problems that the world faced recently is viral
respiratory pathogens. Marine creatures, including Echinodermata, specially Asteroidea …

The rise of coronavirus (COVID-19) cases worldwide has driven the need to discover and
develop novel therapeutics with superior efficacy to treat this disease. This study aims to …