A Perspective of the Amide Group Containing FDA Approved Anticancer Drugs from 2021–2022 (A Review)

M Asif, R Srivastava, A Fatima, M Shakeel… - Russian Journal of …, 2023 - Springer
In this review, we describe a collection and assessment of 16 anticancer drugs approved by
the US FDA between 2021 to June 2022, which include small and big amide group …

Suboptimal antimicrobial stewardship in the COVID-19 era: is humanity staring at a postantibiotic future?

O Owoicho, K Tapela, AL Djomkam Zune… - Future …, 2021 - Taylor & Francis
In the absence of potent antimicrobial agents, it is estimated that bacterial infections could
cause millions of deaths. The emergence of COVID-19, its complex pathophysiology and the …

Nitrogen-doped graphene-based sensor for electrochemical detection of piroxicam, a NSAID drug for COVID-19 patients

C Varodi, M Coros, F Pogăcean, A Ciorîţă, A Turza… - Chemosensors, 2022 - mdpi.com
Nitrogen-doped graphene (NGr) was synthesized by the hydrothermal method using urea as
a reducing and doping agent for graphene oxide (GO). The crystalline structure of GO was …

Injectable niclosamide nanohybrid as an anti-SARS-CoV-2 strategy

NS Rejinold, H Piao, G Jin, G Choi, JH Choy - Colloids and Surfaces B …, 2021 - Elsevier
COVID-19 is a rapidly evolving emergency, which necessitates scientific community to come
up with novel formulations that could find quick relief to the millions affected around the …

Synergistic anti-SARS-CoV-2 activity of repurposed anti-parasitic drug combinations

K Jitobaom, C Boonarkart, S Manopwisedjaroen… - BMC Pharmacology and …, 2022 - Springer
Background COVID-19 pandemic has claimed millions of lives and devastated the health
service system, livelihood, and economy in many countries worldwide. Despite the …

Chemoinformatic analysis of psychotropic and antihistaminic drugs in the light of experimental anti-SARS-CoV-2 activities

BO Villoutreix, R Krishnamoorthy… - … and applications in …, 2021 - Taylor & Francis
Introduction There is an urgent need to identify therapies that prevent SARS-CoV-2 infection
and improve the outcome of COVID-19 patients. Objective Based upon clinical observations …

Structural-Based Virtual Screening of FDA-Approved Drugs Repository for NSP16 Inhibitors, Essential for SARS-COV-2 Invasion Into Host Cells: Elucidation From MM …

S Kumar, H Singh, M Prajapat… - … and Biology Insights, 2023 - journals.sagepub.com
NSP16 is one of the structural proteins of the severe acute respiratory syndrome coronavirus-
2 (SARS-CoV-2) necessary for its entrance to the host cells. It exhibits 2'O-methyl …

In vitro and in vivo antiviral studies of new heteroannulated 1, 2, 3-triazole glycosides targeting the neuraminidase of influenza A viruses

O Kutkat, A Kandeil, Y Moatasim, YAMM Elshaier… - Pharmaceuticals, 2022 - mdpi.com
There is an urgent need to develop and synthesize new anti-influenza drugs with activity
against different strains, resistance to mutations, and suitability for various populations …

Potential role of PIM1 inhibition in the treatment of SARS-CoV-2 infection

MMF Ismail, RR El-Awady, AM Farrag… - Journal of Genetic …, 2023 - Springer
Background SARS-CoV-2 infection involves disturbing multiple molecular pathways related
to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be …

Synthesis and spectroscopic study of novel mixed ligand formula “Artemisinin/Zn” and assessment of its inhibitory effect against “SARS-CoV-2 ″

FA Al-Salmi, SM El-Megharbel, RZ Hamza - Heliyon, 2023 - cell.com
Background Herein, a newly synthesised mixed ligand artemisinin/zinc (Art/Zn) is chemically
characterised and examined against SARS-CoV-2. Methods The synthesised complex was …