Role of CCL2/CCR2 axis in the pathogenesis of COVID-19 and possible Treatments: All options on the Table
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …
Autoantibodies to interferons in infectious diseases
E Quiros-Roldan, A Sottini, SG Signorini, F Serana… - Viruses, 2023 - mdpi.com
Anti-cytokine autoantibodies and, in particular, anti-type I interferons are increasingly
described in association with immunodeficient, autoimmune, and immune-dysregulated …
described in association with immunodeficient, autoimmune, and immune-dysregulated …
COVID-19 inflammation and implications in drug delivery
Growing evidence indicates that hyperinflammatory syndrome and cytokine storm observed
in COVID-19 severe cases are narrowly associated with the disease's poor prognosis …
in COVID-19 severe cases are narrowly associated with the disease's poor prognosis …
Ultrasensitive detection of interleukin 6 by using silicon nanowire field-effect transistors
Interleukin 6 (IL-6) has been regarded as a biomarker that can be applied as a predictor for
the severity of COVID-19-infected patients. The IL-6 level also correlates well with …
the severity of COVID-19-infected patients. The IL-6 level also correlates well with …
The role of platelets, neutrophils and endothelium in COVID-19 infection
E Falcinelli, E Petito, P Gresele - Expert Review of Hematology, 2022 - Taylor & Francis
Introduction COVID-19 is associated to an increased risk of thrombosis, as a result of a
complex process that involves the activation of vascular and circulating cells, the release of …
complex process that involves the activation of vascular and circulating cells, the release of …
[HTML][HTML] Humulus lupus extract rich in xanthohumol improves the clinical course in critically ill COVID-19 patients
W Dabrowski, M Gagos, D Siwicka-Gieroba… - Biomedicine & …, 2023 - Elsevier
Background The systemic inflammatory response following severe COVID-19 is associated
with poor outcomes. Several anti-inflammatory medications have been studied in COVID-19 …
with poor outcomes. Several anti-inflammatory medications have been studied in COVID-19 …
Celecoxib microparticles for inhalation in COVID-19-related acute respiratory distress syndrome
MC Villa-Hermosilla, S Negro, E Barcia, C Hurtado… - Pharmaceutics, 2022 - mdpi.com
Inhalation therapy is gaining increasing attention for the delivery of drugs destined to treat
respiratory disorders associated with cytokine storms, such as COVID-19. The pathogenesis …
respiratory disorders associated with cytokine storms, such as COVID-19. The pathogenesis …
Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators
Abstract Fatal “cytokine storms (CS)” observed in critically ill COVID-19 patients are
consequences of dysregulated host immune system and over-exuberant inflammatory …
consequences of dysregulated host immune system and over-exuberant inflammatory …
[HTML][HTML] Identifying potential pharmacological targets and molecular pathways of Meliae cortex for COVID-19 therapy
Coronavirus disease-19 (COVID-19), caused by SARS-CoV-2, has contributed to a
significant increase in mortality. Proinflammatory cytokine-mediated cytokine release …
significant increase in mortality. Proinflammatory cytokine-mediated cytokine release …
COVID-19: A novel holistic systems biology approach to predict its molecular mechanisms (in vitro) and repurpose drugs
M Sameni, SA Mirmotalebisohi, S Dadashkhan… - DARU Journal of …, 2023 - Springer
Purpose COVID-19 strangely kills some youth with no history of physical weakness, and in
addition to the lungs, it may even directly harm other organs. Its complex mechanism has led …
addition to the lungs, it may even directly harm other organs. Its complex mechanism has led …