Disturb mitochondrial associated proteostasis: Neurodegeneration and imperfect ageing

YA Jagtap, P Kumar, S Kinger, AR Dubey… - Frontiers in Cell and …, 2023 - frontiersin.org
The disturbance in mitochondrial functions and homeostasis are the major features of
neuron degenerative conditions, like Parkinson's disease, Amyotrophic Lateral Sclerosis …

Panax japonicus CA Meyer: a comprehensive review on botany, phytochemistry, pharmacology, pharmacokinetics and authentication

Y Chen, M Liu, J Wen, Z Yang, G Li, Y Cao, L Sun… - Chinese Medicine, 2023 - Springer
Background Panax japonicu s CA Meyer (Zhujieshen) is widely used in traditional medicine
as a tonic hemostatic and anti-inflammatory agent in China, Japan, and Korea. Furthermore …

Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota

X Peng, M Hao, Y Zhao, Y Cai, X Chen, H Chen… - Phytomedicine, 2021 - Elsevier
Background Panax ginseng (PG) and red ginseng (RG) are considered to be effective anti-
aging treatments. However, evidence of their therapeutic mechanisms and difference in anti …

Herbal/natural compounds resist hallmarks of brain aging: From molecular mechanisms to therapeutic strategies

J Qiao, C Wang, Y Chen, S Yu, Y Liu, S Yu, L Jiang… - Antioxidants, 2023 - mdpi.com
Aging is a complex process of impaired physiological integrity and function, and is
associated with increased risk of cardiovascular disease, diabetes, neurodegeneration, and …

Exploring role of natural compounds in molecular alterations Associated with Brain Ageing: a perspective towards Nutrition for Ageing Brain

N Siddiqui, A Sharma, A Kesharwani… - Ageing Research …, 2024 - Elsevier
Aging refers to complete deterioration of physiological integrity and function. By midcentury,
adults over 60 years of age and children under 15 years will begin to outnumber people in …

[HTML][HTML] Total saponins from Panax japonicus promote lipolysis of aging fat through the tyrosine hydroxylase signaling pathway

M Xue, W Wu, G Zhou, J Zhang, S Wang, Y Hu… - Journal of Functional …, 2024 - Elsevier
Aging and obesity are closely related. A key change in the adipose tissue during the aging
process is the decline of lipolysis. The excitation of the sympathetic nerve system is a key …

Zingiberensis Newsaponin Inhibits the Malignant Progression of Hepatocellular Carcinoma via Suppressing Autophagy Moderated by the AKR1C1‐Mediated JAK2 …

K He, X Liu, S Cheng, P Zhou - … ‐Based Complementary and …, 2021 - Wiley Online Library
Objective. Saponins are a group of compounds from various plants, which exhibit an
anticancer activity. This study aimed to explore the anticancer effect of zingiberensis …

The role of Foxo3a in neuron-mediated cognitive impairment

Q LIU, B Yao, G Wu, X Wang, X Xiong… - Frontiers in Molecular …, 2024 - frontiersin.org
Cognitive impairment (COI) is a prevalent complication across a spectrum of brain disorders,
underpinned by intricate mechanisms yet to be fully elucidated. Neurons, the principal cell …

Saponins from Panax japonicus improve neuronal mitochondrial injury of aging rats

C Fan, JX Wang, ZE Xiong, SS Hu, AJ Zhou… - Pharmaceutical …, 2023 - Taylor & Francis
Context Panax japonicus is the dried rhizome of Panax japonicus CA Mey.(Araliaceae).
Saponins from Panax japonicus (SPJ) exhibit anti-oxidative and anti-aging effects. Objective …

Natural bioactive compounds as potential sources for alleviation and treatment of androgenetic alopecia: A research advance

C Fang, H Yang, J Hui, D Fan, J Deng - eFood, 2024 - Wiley Online Library
Alopecia is a common chronic skin disease, which can be categorized as androgenetic
alopecia (AGA), scarring line alopecia, genetic alopecia, and chemical alopecia due to the …