Estrogen receptor function: impact on the human endometrium

K Yu, ZY Huang, XL Xu, J Li, XW Fu… - Frontiers in …, 2022 - frontiersin.org
The physiological role of estrogen in the female endometrium is well established. On the
basis of responses to steroid hormones (progesterone, androgen, and estrogen), the …

Estrogen receptor signaling mechanisms

N Fuentes, P Silveyra - Advances in protein chemistry and structural …, 2019 - Elsevier
The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

Sex hormones in acquired immunity and autoimmune disease

VR Moulton - Frontiers in immunology, 2018 - frontiersin.org
Women have stronger immune responses to infections and vaccination than men.
Paradoxically, the stronger immune response comes at a steep price, which is the high …

Hypothalamic–pituitary–adrenal and hypothalamic–pituitary–gonadal axes: sex differences in regulation of stress responsivity

MG Oyola, RJ Handa - stress, 2017 - Taylor & Francis
Gonadal hormones play a key role in the establishment, activation, and regulation of the
hypothalamic–pituitary–adrenal (HPA) axis. By influencing the response and sensitivity to …

Sex differences in the hypothalamic–pituitary–adrenal axis' response to stress: an important role for gonadal hormones

AL Heck, RJ Handa - Neuropsychopharmacology, 2019 - nature.com
The hypothalamic–pituitary–adrenal (HPA) axis, a neuroendocrine network that controls
hormonal responses to internal and external challenges in an organism's environment …

Role of estrogens in the regulation of liver lipid metabolism

BT Palmisano, L Zhu, JM Stafford - Sex and gender factors affecting …, 2017 - Springer
Before menopause, women are protected from atherosclerotic heart disease associated with
obesity relative to men. Sex hormones have been proposed as a mechanism that …

Sex and gender differences in myocarditis and dilated cardiomyopathy: an update

DL Fairweather, DJ Beetler, N Musigk… - Frontiers in …, 2023 - frontiersin.org
In the past decade there has been a growing interest in understanding sex and gender
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …

Hormonal treatments for major depressive disorder: state of the art

JB Dwyer, A Aftab, R Radhakrishnan… - American Journal of …, 2020 - Am Psychiatric Assoc
Major depressive disorder is a common psychiatric disorder associated with marked
suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …

The role of estrogens in control of energy balance and glucose homeostasis

F Mauvais-Jarvis, DJ Clegg, AL Hevener - Endocrine reviews, 2013 - academic.oup.com
Estrogens play a fundamental role in the physiology of the reproductive, cardiovascular,
skeletal, and central nervous systems. In this report, we review the literature in both rodents …

Endocrine resistance in hormone receptor positive breast cancer–from mechanism to therapy

A Rani, J Stebbing, G Giamas, J Murphy - Frontiers in endocrinology, 2019 - frontiersin.org
The importance and role of the estrogen receptor (ER) pathway has been well-documented
in both breast cancer (BC) development and progression. The treatment of choice in women …