[HTML][HTML] Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

[HTML][HTML] Role of imbalanced gut microbiota in promoting CRC metastasis: from theory to clinical application

S Fan, L Zhou, W Zhang, D Wang, D Tang - Cell Communication and …, 2024 - Springer
Metastasis poses a major challenge in colorectal cancer (CRC) treatment and remains a
primary cause of mortality among patients with CRC. Recent investigations have elucidated …

Immune mechanisms targeting malaria transmission: opportunities for vaccine development

GP Bansal, N Kumar - Expert Review of Vaccines, 2024 - Taylor & Francis
Introduction Malaria continues to remain a major global health problem with nearly a quarter
of a billion clinical cases and more than 60,000 deaths in 2022. There has been significant …

New Ca2+ based anticancer nanomaterials trigger multiple cell death targeting Ca2+ homeostasis for cancer therapy

J Liu, Y Xie, J Ma, H Chu - Chemico-Biological Interactions, 2024 - Elsevier
Abstract Calcium ion (Ca 2+) is a necessary element for human and Ca 2+ homeostasis
plays important roles in various cellular process and functions. Recent reaches have …

“Find Me” and “Eat Me” signals: tools to drive phagocytic processes for modulating antitumor immunity

L Xiao, L Zhang, C Guo, Q Xin, X Gu… - Cancer …, 2024 - Wiley Online Library
Phagocytosis, a vital defense mechanism, involves the recognition and elimination of foreign
substances by cells. Phagocytes, such as neutrophils and macrophages, rapidly respond to …

[HTML][HTML] Pilot Study of the Total and Phosphorylated Tau Proteins in Early-Stage Multiple Sclerosis

I Masiulienė, K Pampuščenko, G Žemgulytė… - Medicina, 2024 - mdpi.com
Background and Objectives: Recent findings suggest that neurodegeneration starts early in
the course of multiple sclerosis (MS) and significantly contributes to the progression of …

A bottom-up approach identifies the antipsychotic and antineoplastic trifluoperazine and the ribose derivative deoxytubercidin as novel microglial phagocytosis …

N Rodriguez-Iglesias, I Paris, J Valero, L Canas-Zabala… - bioRxiv, 2024 - biorxiv.org
Phagocytosis is an indispensable function of microglia, the brain professional phagocytes.
Microglia are particularly efficient phagocytosing cells that undergo programmed cell death …

Studying Microglia-Mediated Neurodegeneration Using Cocultures

T Birkle - 2024 - repository.cam.ac.uk
Microglia are resident innate immune cells of the central nervous system with potent
phagocytic and inflammatory capabilities. These cells are crucial in both health and disease …

[PDF][PDF] DEBRECEN, 2024

N Tarban - dea.lib.unideb.hu
Following skeletal muscle injury, the regeneration begins with local inflammation, which is
accompanied by the removal of dead cells. Phagocytosis of dead cells regulates the …

[图书][B] Perinatal brain damage-phagoptosis and neuroprotection

A Jonsdotter - 2024 - gupea.ub.gu.se
Background: Neonatal encephalopathy is a serious outcome in term infants affecting 1-
2/1000 live births and is often caused by perinatal hypoxia-ischemia (HI). However, brain …