[图书][B] Evaluating the Causal Effect of Mitochondrial Dysfunction on Alzheimer's Disease and Related Dementias Using Latent Heritable Confounder Mendelian …
BD Alvarez - 2023 - search.proquest.com
Alzheimer's disease (AD) is a common and increasingly prevalent form of dementia, for
which there is no disease modifying therapy despite numerous attempts to validate the …
which there is no disease modifying therapy despite numerous attempts to validate the …
FH-like protein 1-Y402H mutation promoted microglial synapse phagocytosis and cognitive impairment in Alzheimer's disease model
Y Cheng, S Chen, R Tao, Z Huang, Q Ye, E Huang - 2023 - researchsquare.com
Background Studies demonstrated that the complement system was involved in the
pathogenesis of Alzheimer's disease (AD). A genetic screening study in a Chinese cohort …
pathogenesis of Alzheimer's disease (AD). A genetic screening study in a Chinese cohort …
Transcriptome-Wide Study of Transcriptional Kinetics in Human Cells
B Jin - 2023 - search.proquest.com
Gene expression from bulk RNA-seq studies is an average measurement between two
chromosomes and across cell populations. Signifcant heterogeneity in gene expression …
chromosomes and across cell populations. Signifcant heterogeneity in gene expression …
[PDF][PDF] Genetic Substrates of Brain Vulnerability and Resilience in APOE2 Mice Transitioning from Midlife to Old Age
A Mahzarnia, HS Moon, J Stout, RJ Anderson, M Strain… - scholar.archive.org
The interplay between genotype, age, and sex may play an important role in determining
successful versus pathological aging. Predicting brain networks vulnerable to age …
successful versus pathological aging. Predicting brain networks vulnerable to age …
Clinicoradiologic Correlates of Corticolimbic Index (CLix) and Glial Activation Differences Among Neuropathologic Subtypes of Alzheimer's Disease: A Retrospective …
N Kouri, I Frankenhauser, Z Peng, SA Labuzan… - papers.ssrn.com
Background: Selective corticolimbic vulnerability to tau pathology in Alzheimer's disease
(AD) underlies clinicopathologic heterogeneity. We aimed to re-express the AD subtype …
(AD) underlies clinicopathologic heterogeneity. We aimed to re-express the AD subtype …
Oleoylethanolamide facilitates PPARa and TFEB signaling and attenuates Ab pathology in a mouse model of Alzheimer's disease
Emerging evidence implicates impaired microglia function and dysregulation of lipid
metabolism in Alzheimer's disease (AD). Oleoylethanolamide (OEA), an endogenous lipid …
metabolism in Alzheimer's disease (AD). Oleoylethanolamide (OEA), an endogenous lipid …