The development of effective antiviral therapy for COVID-19 is critical for those awaiting
vaccination, as well as for those who do not respond robustly to vaccination. This review …

The emergence of severe acute respiratory syndrome (SARS-CoV-2) in 2019 marked the
third occurrence of a highly pathogenic coronavirus in the human population since 2003. As …

Background/aim: Currently there is not an effective antiviral treatment for COVID-19, but a
large number of drugs have been evaluated since the beginning of the pandemic, and many …

This review makes a critical evaluation of 61 peer‐reviewed manuscripts that use a docking
step in a virtual screening (VS) protocol to predict SARS‐CoV‐2 M‐pro (M‐pro) inhibitors in …

Decoy receptor proteins that trick viruses to bind to them should be resistant to viral escape
because viruses that require entry receptors cannot help but bind decoy receptors …

Hesperidin and hesperetin are flavonoids that are abundantly present as constituents of
citrus fruits. These compounds have attracted attention as several computational methods …

Opuntia ficus-indica is a cactaceous plant native to America but, nowadays, widely found
worldwide, having been the most common domesticated species of cactus grown as a crop …

The SARS-CoV-2 pandemic is currently causing an unprecedented global health
emergency since its emergence in December 2019. In December 2021, the FDA granted …

SARS‐CoV‐2 interacting with its receptor, angiotensin‐converting enzyme 2 (ACE2), turns
the host response to viral infection into a dysregulated uncontrolled inflammatory response …

In this review, we collected 1765 severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) M-pro inhibitors from the bibliography and other sources, such as the COVID …