The development of integrative methods is one of the main challenges in bioinformatics.
Network-based methods for the analysis of multiple gene-centered datasets take into …

A mechanistic understanding of the natural aging process, which is distinct from aging‐
related disease mechanisms, is essential for developing interventions to extend lifespan or …

Mesenchymal stem cells (MSCs) are of great clinical interest as a form of allogenic therapy
due to their excellent regenerative and immunomodulatory effects for various therapeutic …

Mass spectrometry (MS) is attractive for single-cell analysis because of its high sensitivity,
rich information, and large dynamic ranges, especially for the single-cell metabolome and …

Translational Bioinformatics (TBI) is defined as the union of translational medicine and
bioinformatics. It emerges as a major advance in science and technology by covering …

Meiosis is a cellular division process that produces gametes for sexual reproduction.
Disruption of complex events throughout meiosis, such as synapsis and homologous …

Cellular heterogeneity plays a pivotal role in tissue homeostasis and the disease
development of multicellular organisms. To deconstruct the heterogeneity, a multitude of …

Biomedical research on the brain has led to many discoveries and developments, such as
understanding human consciousness and the mind and overcoming brain diseases …

Lung transplantation remains the only viable option for individuals suffering from end-stage
lung failure. However, a number of current limitations exist including a continuing shortage …

Prokaryotes encounter constant and often brutal modifications to their environment. In order
to survive, they need to maintain fitness, which includes adapting their protein expression …