[HTML][HTML] Role of antioxidant natural products in management of infertility: a review of their medicinal potential

S Noh, A Go, DB Kim, M Park, HW Jeon, B Kim - Antioxidants, 2020 - mdpi.com
Infertility, a couple's inability to conceive after one year of unprotected regular intercourse, is
an important issue in the world. The use of natural products in the treatment of infertility has …

[HTML][HTML] Apoptosis, inflammation, and oxidative stress in infertility: A mini review

OA Ojo, PI Nwafor-Ezeh, DE Rotimi, M Iyobhebhe… - Toxicology Reports, 2023 - Elsevier
Infertility has been a major issue in our society for many years, and millions of couples all
over the world are still experiencing it. There are several reasons for and causes of infertility …

[HTML][HTML] Doxorubicin-induced alterations in kidney functioning, oxidative stress, DNA damage, and renal tissue morphology; Improvement by Acacia hydaspica tannin …

T Afsar, S Razak, A Almajwal, D Al-Disi - Saudi journal of biological …, 2020 - Elsevier
Doxorubicin (DOX) is an anthracycline drug used for cancer treatment. However, its
treatment is contiguous with toxic effects. We examined the nephroprotective potential of A …

[HTML][HTML] Activation of MT1/MT2 to protect testes and leydig cells against cisplatin-induced oxidative stress through the SIRT1/Nrf2 signaling pathway

J Zhang, Y Fang, D Tang, X Xu, X Zhu, S Wu, H Yu… - Cells, 2022 - mdpi.com
There is growing concern that chemotherapy drugs can damage Leydig cells and inhibit the
production of testosterone. Increasing evidence shows that melatonin benefits the …

Tadalafil alleviates cisplatin-induced reproductive toxicity through the activation of the Nrf2/HO-1 pathway and the inhibition of oxidative stress and apoptosis in male …

BA Abdel-Wahab, SA Alkahtani, EAM Elagab - Reproductive Toxicology, 2020 - Elsevier
Highlights•Tadalafil mitigated cisplatin-induced testicular toxicity in male rats.•Tadalafil
antagonized cisplatin-induced oxidative stress and inflammatory markers.•Tadalafil acts by …

[HTML][HTML] Ameliorative effects of rutin against cisplatin-induced reproductive toxicity in male rats

S Jahan, A Munawar, S Razak, S Anam, QU Ain… - BMC urology, 2018 - Springer
Background Cisplatin (CP) or cis-diammine dichloroplatinum (II) is a platinum based
standard antineoplastic drug which is used against variety of solid tumors and neoplasms …

Review on oxidative stress relation on COVID-19: Biomolecular and bioanalytical approach

M Ebrahimi, P Norouzi, H Aazami… - International journal of …, 2021 - Elsevier
COVID-19 disease has put life of people in stress worldwide from many aspects. Since the
virus has mutated in absolutely short period of time the challenge to find a suitable vaccine …

[HTML][HTML] The protective effect of crocin on cisplatin-induced testicular impairment in rats

B Mesbahzadeh, M Hassanzadeh-Taheri, M Aliparast… - Bmc Urology, 2021 - Springer
Background Side effects of cisplatin (CIS) such as testicular toxicity restrict its clinical use.
Instead, evidence indicates that crocin (CR) has synergistic anti-cancer potential with CIS …

[HTML][HTML] Effect of Acacia hydaspica R. Parker extract on lipid peroxidation, antioxidant status, liver function test and histopathology in doxorubicin treated rats

T Afsar, S Razak, A Almajwal - Lipids in Health and Disease, 2019 - Springer
Background Doxorubicin (DOX) is an anthracycline agent mostly prescribed for various
cancers. However, its treatment is contiguous with toxic effects. Acacia hydaspica prevented …

[HTML][HTML] The mechanistic perspective of bilobetin protective effects against cisplatin-induced testicular toxicity: Role of Nrf-2/Keap-1 signaling, inflammation, and …

WA Negm, AH El-Kadem, IA Hussein, MJ Alqahtani - Biomedicines, 2022 - mdpi.com
Cisplatin (CP) is a productive anti-tumor used to treat numerous tumors. However, multiple
toxicities discourage prolonged use, especially toxicity on the reproductive system. This …