Anosmia in COVID-19: underlying mechanisms and assessment of an olfactory route to brain infection

R Butowt, CS von Bartheld - The Neuroscientist, 2021 - journals.sagepub.com
In recent months it has emerged that the novel coronavirus—responsible for the COVID-19
pandemic—causes reduction of smell and taste in a large fraction of patients. The …

Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms

R Butowt, K Bilinska, CS von Bartheld - Trends in Neurosciences, 2023 - cell.com
The mechanisms of olfactory dysfunction in COVID-19 are still unclear. In this review, we
examine potential mechanisms that may explain why the sense of smell is lost or altered …

Prognosis and persistence of smell and taste dysfunction in patients with covid-19: meta-analysis with parametric cure modelling of recovery curves

BKJ Tan, R Han, JJ Zhao, NKW Tan, ESH Quah… - bmj, 2022 - bmj.com
Objective To clarify in patients with covid-19 the recovery rate of smell and taste, proportion
with persistent dysfunction of smell and taste, and prognostic factors associated with …

Olfactory dysfunction in COVID-19: pathology and long-term implications for brain health

RL Doty - Trends in Molecular Medicine, 2022 - cell.com
Decreased smell function is related to brain health, future mortality, and quality of life. Most
people inflicted with the SARS-CoV-2 virus evidence some measurable smell dysfunction …

[HTML][HTML] Anosmia and dysgeusia in SARS-CoV-2 infection: incidence and effects on COVID-19 severity and mortality, and the possible pathobiology mechanisms-a …

E Mutiawati, M Fahriani, SS Mamada, JK Fajar… - …, 2021 - ncbi.nlm.nih.gov
Background: The present study aimed to determine the global prevalence of anosmia and
dysgeusia in coronavirus disease 2019 (COVID-19) patients and to assess their association …

Why does the omicron variant largely spare olfactory function? Implications for the pathogenesis of anosmia in coronavirus disease 2019

R Butowt, K Bilińska… - The Journal of infectious …, 2022 - academic.oup.com
The omicron variant of severe acute respiratory syndrome coronavirus 2 causes much less
olfactory dysfunction than the previous variants. There are several potential mechanisms for …

The olfactory nerve is not a likely route to brain infection in COVID-19: a critical review of data from humans and animal models

R Butowt, N Meunier, B Bryche, CS von Bartheld - Acta neuropathologica, 2021 - Springer
One of the most frequent symptoms of COVID-19 is the loss of smell and taste. Based on the
lack of expression of the virus entry proteins in olfactory receptor neurons, it was originally …

SARS-CoV-2 and the nervous system: from clinical features to molecular mechanisms

M Pennisi, G Lanza, L Falzone, F Fisicaro… - International journal of …, 2020 - mdpi.com
Increasing evidence suggests that Severe Acute Respiratory Syndrome-coronavirus-2
(SARS-CoV-2) can also invade the central nervous system (CNS). However, findings …

COVID-19 related olfactory dysfunction

K Karamali, M Elliott, C Hopkins - Current opinion in …, 2022 - journals.lww.com
COVID-19 related olfactory dysfunction : Current Opinion in Otolaryngology & Head and Neck
Surgery COVID-19 related olfactory dysfunction : Current Opinion in Otolaryngology & Head …

Prevalence of olfactory dysfunction with the omicron variant of SARS-CoV-2: a systematic review and meta-analysis

CS von Bartheld, L Wang - Cells, 2023 - mdpi.com
The omicron variant is thought to cause less olfactory dysfunction than previous variants of
SARS-CoV-2, but the reported prevalence differs greatly between populations and studies …