Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …

Over 30 million people suffer from the consequences of ischemic stroke. The precise
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …

The retina and brain share similar neurochemistry and neurodevelopmental origins, with the
retina, often viewed as a “window to the brain.” With retinal measures of structure and …

Recent studies have demonstrated that neuroplasticity, such as synaptic plasticity and
neurogenesis, exists throughout the normal lifespan but declines with age and is …

Background Neuroinflammatory factors, especially chemokines, have been widely reported
to be involved in the pathogenesis of Alzheimer's disease (AD). It is unclear how …

Alzheimer's disease (AD) is an age-related progressive neurodegenerative disorder that
leads to cognitive impairment and memory loss. Emerging evidence suggests that …

A hallmark of Alzheimer's disease (AD) are the proteinaceous aggregates formed by the
amyloid-beta peptide (Aβ) that is deposited inside the brain as amyloid plaques. The …

Alzheimer's disease (AD) is the most prevalent age-related neurodegenerative disease,
which has a high heritability of up to 79%. Exploring the genetic basis is essential for …

Background: The concept of Alzheimer disease (AD)—since its histological discovery by
Alzheimer to the present day—has undergone substantial modifications. Methods: We …

Objective: L-carnitine (LC), a vital nutritional supplement, plays a crucial role in myocardial
health and exhibits significant cardioprotective effects. LC, being the principal constituent of …